Accuracy of electrocardiography in diagnosis of left ventricular hypertrophy in arterial hypertension: systematic review

Pewsner, Daniel; Jüni, Peter; Egger, Matthias; Battaglia, Milva; Sundström, Johan; Bachmann, Lucas M.

doi:10.1136/bmj.39276.636354.ae

Cited by 273 publications

(204 citation statements)

References 33 publications

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“…31 ECHO LVH and ECG LVH have been shown to predict mortality independently of each other, 32 and anatomical ECHO LVH and electrical ECG LVH might reflect a different pathogenesis. 1,[30][31][32] The present data support the clinical utility of ECG LVH positivity determined using Sokolow-Lyon voltage criteria and that it should be used in addition to other methods for assessing the CVD risk. If ECG is detecting LVH in overweight subjects, it is a good predictor of mortality.…”

Section: Strengths and Limitationssupporting

confidence: 74%

“…The absence of ECG LVH by the Sokolow-Lyon criterion does not exclude the presence of anatomical LVH. [13][14][15]30 Therefore, ECG test possibly cannot be used only as a surrogate of ECHO in detecting or excluding anatomical LVH. 31 ECHO LVH and ECG LVH have been shown to predict mortality independently of each other, 32 and anatomical ECHO LVH and electrical ECG LVH might reflect a different pathogenesis.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

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Left ventricular hypertrophy by Sokolow-Lyon voltage criterion predicts mortality in overweight hypertensive subjects

et al. 2008

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In view of the low sensitivity of Sokolow-Lyon voltage criteria in the assessment of electrocardiographic left ventricular hypertrophy (ECG LVH) in overweight subjects, we determined its clinical utility in 1840 lean and 3555 overweight subjects with hypertension. They were followed prospectively over an average of 11 years by the Department of Health and Social Security Hypertension Care Computer Project. LVH was determined at baseline using the Sokolow-Lyon criterion that is, the amplitude voltage SV1 þ (max RV5 or RV6) X3.5 mV. Overweight status was defined as body mass index (BMI) X25 kg m À2 . Prevalence of ECG LVH was 16% in lean and 12% in overweight women, 35 and 20% in lean and overweight men. For each 0.1 mV increase in ECG voltage as a continuous variable, the age and sex adjusted risk of stroke, coronary heart disease and cardiovascular disease (CVD) mortality increased significantly by 3.0, 1.5 and 1.8% in overweight subjects and by 2.8, 1.8 and 2.4% in lean subjects. After additional adjustments for smoking, blood glucose and serum cholesterol concentration in a subgroup of 654 lean and 1281 overweight subjects with complete information on these variables, an increasing voltage still significantly predicted stroke and CVD mortality in overweight subjects. The excess high risk of dying was evident especially in women with LVH in the highest BMI quartiles. When ECG detects LVH in overweight subjects, it is a good predictor of mortality despite the lower sensitivity in this group.

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Section: Strengths and Limitationssupporting

confidence: 74%

Section: Strengths and Limitationsmentioning

confidence: 99%

Left ventricular hypertrophy by Sokolow-Lyon voltage criterion predicts mortality in overweight hypertensive subjects

et al. 2008

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“…13 Echocardiography (ECO) is the imaging method with the greatest body of evidence proving its usefulness in clinical practice and research protocols. Traditionally, M-mode, two-dimensional, and Doppler ECO provide a detailed analysis of heart anatomy, diagnose dysfunction (even subclinical), and provide substitutive markers of cardiovascular outcomes for prognosis and intervention studies.…”

Section: Assessment Of Cardiomyopathy In Ckdmentioning

confidence: 99%

Avaliação e manejo da doença cardiovascular em pacientes com doença renal crônica

Bucharles¹,

Varela²,

Barberato³

et al. 2010

J. Bras. Nefrol.

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Cardiovascular disease is the leading cause of death in the set of chronic kidney disease (CKD) patients, whether on renal replacement therapy or conservative treatment. A better understanding of cardiovascular risk factors, diagnostic approach and management are central keys to develop strategies to reduce cardiovascular mortality among those patients. This review article discusses some aspects of pathophysiology, investigation methods and current treatment of cardiovascular disease in CKD patients.

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“…Наличие ГЛЖ явля-ется значимым и независимым предиктором сер-дечно-сосудистых осложнений и смерти [1]. Основ-ным методом диагностики ГЛЖ в настоящее время является ЭхоКГ, имеющая почти 90% чувствитель-ность в измерении индекса массы миокарда (ИММ) левого желудочка (ЛЖ) [2]. Тогда как электрокардио-графия (ЭКГ) являющаяся частью рутинного обсле-дования всех больных АГ, обладает небольшой чув-ствительностью в выявлении ГЛЖ [3].…”

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Prediction Role of the Left Ventricle Remodelling in Arterial Hypertension Patients

Иванова¹,

Васюк²,

Shkolnik³

et al. 2016

Russ J Cardiol

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Цель. Изучение влияния различных геометрических моделей левого желу-дочка (ЛЖ) на долгосрочных прогноз у больных артериальной гипертензией (АГ). Материал и методы. 180 больных АГ в возрасте 50,5±6,7 лет в течение 10 летнего наблюдения. Всем пациентам на этапе включения проводилось стандартное клинико-функциональное обследование, двумерная эхокар-диография (ЭхоКГ), тест 6-минутной ходьбы, определение уровня NTproBNP. Результаты. По данным ЭхоКГ гипертрофия ЛЖ (ГЛЖ) выявлялась в 1,8 раза чаще, чем по данным электрокардиографии (ЭКГ). Нормальная геометрия ЛЖ выявлена у 25,5%, концентрическое ремоделирование ЛЖ -20,0%, концен-трическая ГЛЖ -42,8%, эксцентрическая ГЛЖ -11,7%. Заключение. По данным многофакторного анализа наличие ГЛЖ являлось независимым предиктором неблагоприятного прогноза и в сочетании с другими независимыми факторами (возраст, мужской пол, результаты теста 6-минутной ходьбы, плазменный уровень NT-proBNP) увеличивало вероятность развития неблагоприятного сердечно-сосудистого события в два раза. PREDICTION ROLE OF THE LEFT VENTRICLE REMODELLING IN ARTERIAL HYPERTENSION PATIENTSIvanova S. V., Vasyuk Yu. A., Shkolnik E. L., Khadzegova A. B., Sinitsina I. A. Aim.To study the influence of various geometric models of the left ventricle (LV) on long-term prognosis in arterial hypertension (AH). Material and methods. Totally, 180 AH patients studied at the age 50,5±6,7 y. o., for 10 years of follow-up. All patients at the inclusion stage underwent standard clinical and functional investigation, 2D-echocardiography, 6-minute walking test, NT-proBNP. Results. By EchoCG the LV hypertrophy (LVH) was found 1,8 times more frequently than by ECG. Normal geometry of the LV was found in 25,5%, concentric LVH -42,8%, eccentric LVH -11,7%. Conclusion. By the multifactorial analysis, LVH was independent predictor of adverse prognosis and, in combination with other independent factors (age, male gender, 6-minute walking test, NT-proBNP level in plasma) did double the probability of an adverse cardiovascular risk. Russ

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Accuracy of electrocardiography in diagnosis of left ventricular hypertrophy in arterial hypertension: systematic review

Cited by 273 publications

References 33 publications

Left ventricular hypertrophy by Sokolow-Lyon voltage criterion predicts mortality in overweight hypertensive subjects

Left ventricular hypertrophy by Sokolow-Lyon voltage criterion predicts mortality in overweight hypertensive subjects

Avaliação e manejo da doença cardiovascular em pacientes com doença renal crônica

Prediction Role of the Left Ventricle Remodelling in Arterial Hypertension Patients

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