Purpose:
To investigate the effect of corneal curvature (K) on the accuracy of 8 IOL formulas in highly myopic eyes.
Setting:
Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Design:
Retrospective consecutive case series.
Methods:
302 eyes (302 patients) were analyzed in subgroups based on the K value. The mean refractive error, mean absolute error (MAE), median absolute error (MedAE), root-mean-square absolute prediction error (RMSAE) and proportions of eyes within ±0.25 Diopter (D), ±0.50 D, ±0.75 D, ±1.00 D were statistical analyzed.
Results:
Emmetropia Verifying Optical (EVO) 2.0, Kane, and Radial Basis Function (RBF) 3.0 had the lower MAE (≤ 0.28) and RMSAE (≤ 0.348) and highest percentage of eyes within ±0.50 D (≥ 83.58%) in the flat (K ≤ 43D) and steep K (K > 45D) groups. Hoffer QST had the lowest MedAE (0.19), RMSAE (0.351) and the highest percentage of eyes within ±0.50 D (82.98%) in the normal K group (43 < K ≤ 45D). When AL ≤ 28 mm, all formulas showed close RMSAE values (0.322 to 0.373) in flat K group. When AL > 28 mm, RBF 3.0 achieved the lowest MAE (≤ 0.24), MedAE (≤ 0.17) and RMSAE (≤ 0.337) across all subgroups.
Conclusions:
EVO 2.0, Kane, and RBF 3.0 were the most accurate in highly myopic eyes with a flat or steep K. Hoffer QST is recommended for long eyes with normal K values. RBF 3.0 showed the highest accuracy when AL > 28 mm, independent of corneal curvature.