Accuracy of Optical Coherence Tomography in the Evaluation of Neointimal Coverage After Stent Implantation

Abstract

Subtle differences in neointimal formation induced by current DES can be reproducibly analyzed in vivo by OCT. However, OCT measurement of stent area seems to have less correlation with histology.

Accuracy of Optical Frequency Domain Imaging for Evaluation of Coronary Adventitial Vasa Vasorum Formation After Stent Implantation in Pigs and Humans – A Validation Study –

“…EEL, external elastic lamina. examining intra-and inter-observer variabilities in the present OFDI measurement, as previously described, 22 confirming the high reproducibility of the measurements (Tables S3,S4). .…”

Delayed Coverage in Malapposed and Side-Branch Struts With Respect to Well-Apposed Struts in Drug-Eluting Stents

“…Although biologically plausible and intuitively accepted by the scientific community, this approach cannot be fully supported by current evidence. OCT coverage correlates with histological neointimal healing and endothelialization after stenting in animal models, [33][34][35] but its sensitivity and specificity in human atherosclerotic vessels are still unknown. OCT is not able to detect thin Values are presented as count (%).…”

Tissue coverage of paclitaxel and sirolimus eluting stents in long term follow-up: Optical coherence tomography study

“…Due to high spatial resolution OCT offers precise measurement of the neointimal thickness and distribution [9]. Additionally OCT enables assessment of tissue coverage of the each stent strut [10,11].…”