“…Main concerns include the age of equations [5-7], study population in terms of genetic and epigenetic influences on body weight, body composition, and long-term influences of dietary patterns [8, 9]. For these reasons, several studies have investigated the validity and accuracy of previously published REE equations in specific/national populations, like in Australians [10], Brazilian postmenopausal women [4], Dutch, German and American overweight and obese adults [11-14], normal weight, overweight and obese Italian women [15, 16], and Spanish obese adult and child populations [17, 18]. In many of these studies, the existing equations failed to predict REE within ±10% of the measurements using indirect calorimetry prompting the development of new population-specific equations.…”