Accuracy of Ultrafiltration Volume Measurements for Patients on Peritoneal Dialysis

Mahon, Althea; Fan, Stanley

doi:10.1177/089686080502500118

Cited by 11 publications

(10 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Peritoneal membrane transport was evaluated from plasma creatinine concentration and a 4‐hour dwell using 2 L of 22.7 g/L glucose peritoneal dialysate 13 . Ultrafiltration (UF) and dialytic sodium removal (DSR) were corrected for flush before fill technique in CAPD patients 14 . Multifrequency bioelectrical impedance (MFBIA) was measured using a standardised protocol (InBody 720, Seoul, South Korea), with dialysate drained out and after voiding 9 .…”

Section: Methodsmentioning

confidence: 99%

Determinants of volume status in peritoneal dialysis: A longitudinal study

Jaques

Davenport

2020

Nephrology

View full text Add to dashboard Cite

Aim In peritoneal dialysis (PD), fluid overload is frequent and associated with cardiac dysfunction and mortality. As it is considered a modifiable risk factor, we wished to describe clinical determinants of fluid overload in a longitudinal cohort of PD outpatients. Methods We consecutively included PD outpatients treated with continuous ambulatory PD (CAPD) or automated PD (APD) attending for their routine clinical visit at a single tertiary hospital. Extracellular water (ECW) to total body water (TBW) ratio was measured by multifrequency bioelectrical impedance. Peritoneal transport characteristics were measured with a standard peritoneal equilibration test. Patients had a second follow‐up visit with the same measurements. Univariable and multivariable mixed linear regression models were conducted with ECW/TBW as the dependent variable. Results A total of 155 patients were enrolled with a median follow‐up time of 12 months. Median dialysis vintage was 13.5 ± 3.4 months. Overall mean value of ECW/TBW was 39.3% ± 1.1. In multivariable analysis, factors positively associated with ECW/TBW were: Age (P < .001), diabetes (P = .002), and SBP (P = .028). Factors negatively associated with ECW/TBW were: nPNA (P = .001), serum albumin (P < .001) and PTH (P = .014). None of the considered variable showed a significant interaction with time. Conclusion We confirm a high prevalence of fluid overload in PD patients and show that it is strongly associated with older age, diabetes, hypoalbuminemia and protein energy wasting. In contrast, when PD prescription is tailored to patient's individual characteristics, residual renal function, PD modality and peritoneal characteristics are not decisive in controlling volume status.

show abstract

Section: Methodsmentioning

confidence: 99%

Determinants of volume status in peritoneal dialysis: A longitudinal study

Jaques

Davenport

2020

Nephrology

View full text Add to dashboard Cite

show abstract

“…I am grateful to Stanley Fan for pointing out the far more simple explanation of our data, that we were failing to account for the overestimation of UF due to overfill in our CAPD patients. He had recently found in a survey of UK units that more than 90% did not routinely account for overfill, and that the average overfill for Baxter and Fresenius fluids in his center was approximately 225 mL (10). Regular audit of overfill in our own unit is in keeping with this amount.…”

mentioning

confidence: 99%

Overfill or Ultrafiltration? We Need to be Clear

Davies

2006

Perit Dial Int

View full text Add to dashboard Cite

“…These findings confirm the results of other authors (2,6,7). However, studies on biocompatible solutions show conflicting results, perhaps because of different methodological approaches; moreover, it is not always reported whether the correction for flush-before-fill (19) or for the over filling of PD bags (20) has been performed. Different solutions were used and UF was evaluated considering either the daily UF or the UF of a fraction of 1 day of treatment, and with PETs lasting 4 hours but using solutions with different glucose concentrations.…”

Section: Discussionmentioning

confidence: 99%

Effects of Ionized Sodium Concentrations on Ultrafiltration Rate in Peritoneal Dialysis Using Lactate and Lactate/Bicarbonate Solutions

et al. 2008

View full text Add to dashboard Cite

Objective To investigate the possible effects of different concentrations of ionized sodium (NaI) on peritoneal ultrafiltration (UF) rate using lactate (Lac) and lactate/bicarbonate (Lac/Bic) dialysis solutions. Design Two random consecutive (after an interval of 48 hours) peritoneal equilibration tests (PETs) were performed in 13 patients (4 males and 9 females) on regular continuous ambulatory peritoneal dialysis (PD) treatment for at least 3 months. Two different PD solutions containing anhydrous glucose 3.86% were used: a 40 mmol/L Lac solution and a 15/25 mmol/L mixed Lac/Bic solution. Concentrations of total sodium (NaT) and NaI were measured by flame photometer and direct ion-selective electrode respectively. Results Dialysate concentrations of NaT were not different during PETs using Lac and Lac/Bic. Dialysate concentrations of NaI in fresh PD solutions were different (133.3 ± 1.7 vs 128.2 ± 3.9 mmol, p < 0.0001); however, these differences disappeared just after the end of the infusion of the fresh solutions. Peritoneal UF rate was not significantly different during PETs using Lac versus Lac/Bic (609 ± 301 mL vs 542 ± 362 mL). The dialysate-to-plasma ratios of sodium concentrations at 60 minutes of the PETs (which are expressions of free water transport) were not different using Lac versus Lac/Bic (0.89 ± 0.04 vs 0.89 ± 0.04 respectively, p = 0.96). All the other classical parameters of the PET were not different between Lac and Lac/Bic. Conclusions The higher dialysate concentrations of NaI due to lower dialysate pH and consequently the higher effective osmolality of the fresh Lac PD solutions did not influence peritoneal UF rate, probably because of the fast reduction of NaI concentrations due to rapid correction of dialysate pH at the end of the infusion of Lac solutions into the peritoneal cavity.

show abstract

Accuracy of Ultrafiltration Volume Measurements for Patients on Peritoneal Dialysis

Cited by 11 publications

References 6 publications

Determinants of volume status in peritoneal dialysis: A longitudinal study

Determinants of volume status in peritoneal dialysis: A longitudinal study

Overfill or Ultrafiltration? We Need to be Clear

Effects of Ionized Sodium Concentrations on Ultrafiltration Rate in Peritoneal Dialysis Using Lactate and Lactate/Bicarbonate Solutions

Contact Info

Product

Resources

About