Accuracy of ultrasonography and fine‐needle aspiration cytology in the diagnosis of prostate diseases in dogs

Abstract

Clinical signs of prostatic diseases in dogs are often non‐specific. Appropriate treatment should be based on a detailed investigation using reliable diagnostic tools. The aim of our study was to evaluate the diagnostic value of ultrasonography (US) and fine‐needle aspiration (FNA) cytology in dogs' prostate diseases. The mean accuracy of FNA cytology and US were 0.72 and 0.88 (n = 13), respectively. US gland size measurements and actual gland dimensions were highly concordant. Obtained results confirm the high diagnostic value of US and FNA biopsy and in prostatic diseases. Diagnosis based on US is highly reliable; however, it should be combined with clinical signs. Therefore, cytological evaluation of prostate gland material may be performed to differentiate or confirm presumptive diagnosis.

Suitability of ultrasound-guided fine-needle aspiration biopsy for transcriptome sequencing of the canine prostate

“…The US-FNA procedure of the prostate was performed using the previously described standard protocol for US-FNA of the canine prostate 69 . Differences of parenchyma echogenicity 3,30 were used for identification and collection of representative samples. The US-FNA samples were processed as the above mentioned the PM-FNA sampling protocol.…”

“…Meeting the requirements of a minimal invasive sampling procedure 2 , aspirates collected by ultrasound-guided fine-needle aspiration (US-FNA) biopsy are regularly employed in the cytological diagnosis of canine prostate diseases 28 and other diagnostic approaches, such as flow cytometric phenotyping 29 . In this context, ultrasonographic parameters such as prostate size and differences in echogenicity within the parenchyma are used to identify lesions 3 and guide the fine-needle to aspirate cells from representative areas 30 . The cells targeted and collected by the US-FNA procedure normally undergo cytological diagnosis 28 , but are also viable for molecular profiling 31,32 .…”

Highlights on the Canine Prostatic Specific Esterase (CPSE): A diagnostic and screening tool in veterinary andrology

“…Serum CPSE assessment improves canine andrological diagnostics and it is useful in order to perform a complete breeding soundness examination of the dog, in addition to the new applications of traditional and doppler ultrasound (De Freitas, Pinto, Silva, & da Silva, 2015; Mantziaras, 2020; Rodak, Dzimira, Podolak, Płóciennik, & Niżański, 2018; Russo, Vignoli, & England, 2012; Zelli, Orlandi, Troisi, Cardinali, & Polisca, 2013).…”

Evaluation of canine prostate volume in calculated tomographic images - comparison of two assessment methods

“…It is an easy to perform and highly specific diagnostic tool for investigating the prostate gland. With ultrasound guidance, fine needle aspiration biopsies are performed safely, resulting in accurate diagnosis [11]. Due to the absence of organ superimposition and less dependence on operator’s experience in comparison to ultrasonography, many studies recommended computed tomography (CT) imaging for investigating the size and tissue morphology of the prostate as well as for allowing characterisation of surrounding structures (e.g.…”

“…Due to the absence of organ superimposition and less dependence on operator’s experience in comparison to ultrasonography, many studies recommended computed tomography (CT) imaging for investigating the size and tissue morphology of the prostate as well as for allowing characterisation of surrounding structures (e.g. sublumbar lymph node assessment) [7, 12–14], especially for scientific studies [11]. However, there is only scant literature available on volumetric measurements of the prostate gland in CT, which might be explained by the necessity of anaesthesia during examination and the limited access to computed tomography in veterinary medicine.…”