Accuracy of whole‐body PET and PET‐CT in initial M staging of head and neck cancer: A meta‐analysis

Abstract

Whole-body PET and PET-CT have good diagnostic performance in initial M staging of head and neck cancer; although PET-CT tends to have higher accuracy than PET.

Diagnostic performance of 18fluorodesoxyglucose positron emission/computed tomography and magnetic resonance imaging in detecting T1‐T2 head and neck squamous cell carcinoma

“…Cervical MRI remains the reference imaging for assessing mandibular invasion of tumor . Furthermore, FDG‐PET/CT offers in a whole‐body single scan a high diagnostic accuracy for M staging and synchronous disease . Moreover, Kyzas et al highlighted in their meta‐analysis the identical diagnostic performance of both techniques in detecting lymph node involvement .…”

Role of fluorine-18 fluorodeoxyglucose PET/CT in head and neck oncology: the point of view of the radiation oncologist

“…59 Table 3 summarizes available studies comparing the performances of different imaging approaches to detect distant metastasis of HNSCC. 52,53,[58][59][60][61][62][63] Globally, all these studies indicate that PET 6 CT is superior to conventional imaging. 18 F-FDG-PET shows higher accuracy (90-95%) than CT for the detection of distant metastasis.…”

“…53 It is noteworthy that early detection of metastasis has a major impact on patient management avoiding unnecessary radical treatments. [54][55][56][57] Xu et al 58 conducted a meta-analysis evaluating the accuracy of PET and PET-CT in the initial M staging of HNSCC. This metaanalysis suggested that 209 (14.4%) of 1445 patients had distant metastasis or a second primary tumour (SPT).…”

Radiographic Imaging of Human Papillomavirus Related Carcinomas of the Oropharynx

“…Head and neck cancer patients are at risk for developing distant metastasis and second primary tumors. PET-CT has been found to have ''good performance'' in M staging of head and neck cancer, and be more effective than CT of the chest and abdomen alone in detection of metastatic lesions [15]. We routinely perform PET scans with CECT, combining anatomic and functional evaluation into one setting.…”