Accurate Estimation of Carotid Luminal Surface Roughness Using Ultrasonic Radio-Frequency Echo

Kitamura, Kosuke; Hasegawa, Hideyuki; Kanai, Hiroshi

doi:10.1143/jjap.51.07gf08

Cited by 23 publications

(29 citation statements)

References 60 publications

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“…To improve the spatial resolution in the measurement of the response of an object to the acoustic radiation force, an ultrasound correlation-based method, the phased-tracking method, 18,19) was used to measure the distribution of minute displacements. The accuracy of the displacement measurement by the phased-tracking method has already been evaluated to be 0.2 µm by basic experiments using a rubber plate 20) and, also, has already been applied to measurements of vibrations and viscoelasticities of the arterial wall 21,22) and heart wall. 23,24) We used two phantoms made of two different polyurethane rubbers that simulate soft biological tissues and another phantom containing porcine muscle tissue to measure the propagation of the shear wave and estimate the viscoelasticity.…”

Section: Acoustic Radiation Pressure At Frequency Difference Of Two Cmentioning

confidence: 99%

Measurement of shear viscoelasticity using dual acoustic radiation pressure induced by continuous-wave ultrasounds

Tachi¹,

Hasegawa²,

Kanai³

2014

Jpn. J. Appl. Phys.

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It is important to evaluate the viscoelasticity of muscle for assessment of its condition. However, quantitative and noninvasive diagnostic methods have not yet been established. In our previous study, we developed a method, which used ultrasonic acoustic radiation forces irradiated from two opposite horizontal directions, for measurement of the viscoelasticity. Using two continuous wave ultrasounds, an object can be actuated with an ultrasonic intensity, which is far lower (0.9 W/cm 2) than that in the case of the conventional acoustic radiation force impulse (ARFI) method. In the present study, in vitro experiments using phantoms made of polyurethane rubber and porcine muscle tissue embedded in a gelatin block were conducted. We actuated phantoms by ultrasonic radiation force and measured the propagation velocity of the generated shear wave inside the phantoms using a diagnostic ultrasound system. The viscoelasticities of phantoms were estimated by fitting a viscoelastic model, i.e., the Voigt model, to the frequency characteristic of the measured shear wave propagation speed. In the mechanical tensile test, a softer polyurethane phantom exhibited a lower elasticity and a higher viscosity than a polyurethane phantom with a higher elasticity and a lower viscosity. The viscoelasticity measured by ultrasound showed the same tendency as that in the tensile test. Furthermore, the viscoelasticity of the phantom with porcine muscular tissue was measured in vitro, and the estimated viscoelasticity agreed well with that reported in the literature. These results show the possibility of the proposed method for noninvasive and quantitative assessment of the viscoelasticity of biological soft tissue.

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Section: Acoustic Radiation Pressure At Frequency Difference Of Two Cmentioning

confidence: 99%

Measurement of shear viscoelasticity using dual acoustic radiation pressure induced by continuous-wave ultrasounds

Tachi¹,

Hasegawa²,

Kanai³

2014

Jpn. J. Appl. Phys.

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“…If an untouchable part can be measured in vivo using a miniaturized tactile sensor quantitatively, as if traced by a finger, it would be possible to obtain new knowledge about living tissue and to establish more accurate diagnosis during minimally invasive surgery. For example, it would be useful to measure the minute surface roughness of the carotid arterial wall to detect an early stage of atherosclerosis, where the luminal surface of the arterial wall becomes rough as a result of endothelial damage [15,16]. Consequently, it could become possible to prevent the occurrence of strokes and heart attacks.…”

Section: Tactile Sensor For Medical Applicationsmentioning

confidence: 99%

“…manufacturing [32]. For the detection of the early stage of atherosclerosis described in "Tactile sensor for medical applications" section, sub-micron resolution is required because endothelial cells are 10-20 μm thick [15]. However, the surface roughness caused by atherosclerosis in the early stage cannot be measured by conventional B-mode imaging using ultrasonography [15].…”

Section: Tactile Sensors Composed Of Organic Ferroelectricsmentioning

confidence: 99%

“…For the detection of the early stage of atherosclerosis described in "Tactile sensor for medical applications" section, sub-micron resolution is required because endothelial cells are 10-20 μm thick [15]. However, the surface roughness caused by atherosclerosis in the early stage cannot be measured by conventional B-mode imaging using ultrasonography [15]. On the other hand, as our thin plate type tactile sensor can evaluate the micro-step heights (more than 10 microns) and surface roughness (Ra: 1.6 to 6.3 microns) [32], the application of PVDF tactile sensors to this diagnosis can be expected although the sensor should be inserted invasively and detect the lesion without the help of any image modalities.…”

Section: Tactile Sensors Composed Of Organic Ferroelectricsmentioning

confidence: 99%

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Development of catheter-type tactile sensor composed of polyvinylidene fluoride (PVDF) film

et al. 2019

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To achieve quantitative palpation in vivo, we developed a catheter-type tactile sensor composed of a polyvinylidene fluoride film for minimally invasive surgery. We evaluated the fundamental performance of the prototype sensor by a weight-drop test. We also measured the output of the prototype sensor as it was inserted into a blood vessel model with shapes mimicking lesions. The ø2-mm sensor passed easily into the blood vessel model with lesion-like shapes. Sensor outputs corresponded to the shape of the inner wall of the blood vessel model, making it possible to determine the position of a protrusion and the convexity interval of a rough surface by filtering and frequency analysis of the output.

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“…23) The phasedtracking method has been used for determining cardiovascular dynamics 24,25) and also for obtaining morphological information. 26,27) The average velocity v(t + ¦T/2) of an object at the frame interval ¦T is accurately estimated using the phase shift between the received ultrasonic pulses as…”

Section: Acquisition Of Ultrasonic Datamentioning

confidence: 99%

Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment

Fujita¹,

Tagashira²,

Hasegawa³

et al. 2014

Jpn. J. Appl. Phys.

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For the realization of noninvasive and regional myocardial tissue characterization, in the present study, we attempted to elucidate the characteristics of the myocardial response to electrical excitation and its propagation by an ex vivo experiment using a rat left ventricular wall. To visualize such a propagation phenomenon, whose speed is up to several m/s, high-frame-rate ultrasound was used to measure the myocardial vibrations driven by electrical excitation at 72 points along the heart wall with 200 µm intervals at a frame rate of 3472 Hz. The propagation of myocardial vibration was visualized by estimating the delay time between vibration waveforms measured in the reference ultrasonic beam and each ultrasonic beam using the cross-correlation function between the vibration waveforms. From the estimated delay time, we visualized the propagation of myocardial vibration caused by electrical excitation. The propagation speed was estimated to be 2.5 m/s in the entire excised myocardium. It was also estimated to be 1.8 m/s in the middle of the heart wall and 2.2 m/s at the internal and external surfaces of the leftventricular wall. The results showed that the myocardial vibration driven by electrical excitation could be measured with high-frame-rate ultrasound.

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Accurate Estimation of Carotid Luminal Surface Roughness Using Ultrasonic Radio-Frequency Echo

Cited by 23 publications

References 60 publications

Measurement of shear viscoelasticity using dual acoustic radiation pressure induced by continuous-wave ultrasounds

Measurement of shear viscoelasticity using dual acoustic radiation pressure induced by continuous-wave ultrasounds

Development of catheter-type tactile sensor composed of polyvinylidene fluoride (PVDF) film

Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment

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