Accurate locomotor activity profiles of group-housed mice derived from home cage monitoring data
Rongwan Sun,
Marie-Christin Gaerz,
Christian Oeing
et al.
Abstract:IntroductionHolistic phenotyping of rodent models is increasing, with a growing awareness of the 3Rs and the fact that specialized experimental setups can also impose artificial restrictions. Activity is an important parameter for almost all basic and applied research areas involving laboratory animals. Locomotor activity, the main form of energy expenditure, influences metabolic rate, muscle mass, and body weight and is frequently investigated in metabolic disease research. Additionally, it serves as an indic… Show more
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