2020
DOI: 10.22541/au.159110364.44447300
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ACEIs, ARBs, Ibuprofen linked to COVID-19: The other side of the broken mirror

Abstract: This article discusses from a pharmacological point of view, the points of weakness in a correspondence published at the Lancet Respiratory Medicine that has suggested a hypothesis relating ACEIs, ARBs and ibuprofen to be associated with a higher risk for COVID-19 infection and complications. This article also explains some unfortunate mistakes that have been made by some who have adopted this hypothesis and decided to unwisely recommend against these important drugs.

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“…This suggestion is contradicting all the current practical approach adopted world-wide that avoided NSAIDs and preferred paracetamol. Noteworthy, the author has fully explained the incident that led to the world to avoid use of ibuprofen 7 and he's also recommended against the routine use of steroids in COVID-19 but suggested to be administered for patients with late acute respiratory syndrome 2 and most recently this suggestion has been proved clinically valid 8…”
mentioning
confidence: 99%
“…This suggestion is contradicting all the current practical approach adopted world-wide that avoided NSAIDs and preferred paracetamol. Noteworthy, the author has fully explained the incident that led to the world to avoid use of ibuprofen 7 and he's also recommended against the routine use of steroids in COVID-19 but suggested to be administered for patients with late acute respiratory syndrome 2 and most recently this suggestion has been proved clinically valid 8…”
mentioning
confidence: 99%