1997
DOI: 10.1046/j.1460-9592.1997.d01-47.x
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Acetaminophen or ketorolac for post myringotomy pain in children? A prospective, double‐blinded comparison

Abstract: Myringotomy with tube placement (BMT) is the most frequent surgical procedure performed in children. The purpose of this prospective, double-blinded study was to determine if 15 mg.kg-1 of acetaminophen (paracetamol) provides analgesia similar to that provided by ketorolac, 1 mg.kg-1, at a lower cost. One-hundred-and-thirty-two children, ages six months to nine years, scheduled for elective BMT were randomized to receive oral acetaminophen or ketorolac 30 min preoperatively. An Objective Pain Scale score was a… Show more

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Cited by 33 publications
(17 citation statements)
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“…It is unlikely that the few extra minutes of sleep in the patients who received midazolam before their sevoflurane allowed significant absorption of acetaminophen. Even if that were so, the benefits of such low‐potency analgesics are difficult to demonstrate in myringotomy patients (18, 19). All things considered, the agitation seen after sevoflurane was not due to pain.…”
Section: Discussionmentioning
confidence: 99%
“…It is unlikely that the few extra minutes of sleep in the patients who received midazolam before their sevoflurane allowed significant absorption of acetaminophen. Even if that were so, the benefits of such low‐potency analgesics are difficult to demonstrate in myringotomy patients (18, 19). All things considered, the agitation seen after sevoflurane was not due to pain.…”
Section: Discussionmentioning
confidence: 99%
“…Oral paracetamol, ibuprofen or diclofenac should be administered 30 minutes prior to the procedure where possible 31. Ketorolac is an alternative nonsteroidal analgesic and has been shown to provide superior immediate postoperative analgesia when compared with paracetamol alone; however, up to 30% of these patients may still require additional analgesia in the immediate postoperative period 31,32. Combinations of paracetamol and a nonsteroidal or intranasal fentanyl have also been studied but in combination do not provide any additional analgesic benefit in the immediate postoperative period 33.…”
Section: Perioperative Carementioning
confidence: 99%
“…Ketorolac 1 mg·kg −1 provides minor improvements in analgesia when compared with low doses of paracetamol, 10 mg·kg −1 (3,8); paracetamol 10 mg·kg −1 + codeine 1 mg·kg −1 (8); and paracetamol 15 mg·kg −1 (but only first 10 min there was no difference at 20 min) (4).…”
Section: 2 Ent Surgerymentioning
confidence: 99%