Acetazolamide and Purpura

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Acetazolamide

“…16,17 In rabbits, its therapeutic index was determined to be 2.7. 18 Although occurring rarely, several, often fatal, blood dyscrasias have been reported in patients taking acetazolamide, 16 including thrombocytopenic purpura, 19 pancytopenia, 20 and aplastic anaemia. 21 …”