Acetic acid production by Acetogenium kivui in continuous culture — kinetic studies and computer simulations

Abstract

This work considers the continuous production of acetic acid by the homoaeetogenic and thermophilic bacterium Acetogeniurn kivui. A mathematical model for the growth kinetics has been developed. The unstructured model for growth and product formation includes product and substrate inhibition as well as maintenance energy effects. The associated model parameters have been identified by non-linear optimization and evidenced experimentally in continuous culture as steady-state data. By using a mineral medium with glucose as the energy and carbon source for the bacteria proper carbon balances are available. The model permits good predictions of steady-state concentrations.

Transforming Waste Cheese-Whey into Acetic Acid through a Continuous Membrane-Integrated Hybrid Process

“…Higher productivity has been reported in some literatures, but those were achieved using an expensive carbon source. In many such cases, − the production process is a batch fermentation one resulting in low productivity (0.66–0.7 g L –1 h –1 ) though a yield of 80–98% has been reported. With the use of additional lactose as feed supplement, the reported maximum yield of acetic acid is 0.55 g g –1 with a productivity of 0.15 g L –1 h –1 where a single stage membrane system was utilized .…”

“…This study shows that by the pH adjustment, product inhibition can be controlled, but the resulting product will be acetate salt instead of direct acetic acid. Another serious attempt was carried out on the production of acetic acid with Acetogenium kivui , from pure glucose. In some cases, the whey lactose was supplemented with additional carbohydrates, , and good acetic acid yield but low productivity was obtained while working in batch mode.…”

Development and analysis of a sustainable technology in manufacturing acetic acid and whey protein from waste cheese whey

“…Those processes not only involve harsh chemicals and highly energy consuming steps like evaporation and distillation but also end up with generation of mixture of waste acids and chemicals (Jim enez et al, 2012). Studies with batch or fed-batch systems employing microfiltration or ultrafiltration membranes in tubular or hollow fiber modules for downstream processing have been reported (Jones, 2000;Esymondt et al, 1990;Grzenia et al, 2008;Rodríguez et al, 2006). But single-step membrane integration does not help in reaping the possible manifold benefits of membrane-integration.…”

Performance of a multistage fermentor with cell filtering and recycling for continuous acetic acid production.

“…In recent years, various attempts to improve the productivity of acetic acid by continuous fermentation have been made (3)(4)(5)(6). One way of obtaining high production rates is to maintain more viable microbial cells in a fermentor compared to conventional batch or continuous production of acetic acid.…”