Acetonuria in Childhood: A Study of Its Prevalency in the Medical Wards of a Children's Hospital; With an Inquiry Into Its Cause.

Frew, R

doi:10.1016/s0140-6736(01)42127-1

Cited by 3 publications

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“…of all children betweeni the ages of 6 to 12 years inclusive. (7) The biochemical picture associated w%ith disturbances of the carbohydrate and fat metabolism, acetonumia, etc., is not more frequently found in ' nervous,' than in other subnormal children. (8) There is no specific biochemical picture peculiar to the ' nervous' child.…”

Section: ) Clinical and Biochemiical Study Of Subnormial Child 161mentioning

confidence: 99%

A Clinical and Biochemical Study of the Subnormal Child

Osman¹,

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1930

Archives of Disease in Childhood

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Section: ) Clinical and Biochemiical Study Of Subnormial Child 161mentioning

confidence: 99%

A Clinical and Biochemical Study of the Subnormal Child

Osman¹,

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1930

Archives of Disease in Childhood

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“…In 1911 Frew(') drew attention to the great frequency of ketonuria in the children recently admitted to the wards of The Hospital for Sick Children, Great Ormond Street. All clinical experience and all experimental work are in accord in recognizing that a significant ketonsmia occurs more readily in childhood than in adult life.…”

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Ketonaemia, Cyclical Vomiting and Some Nervous Disturbances in Children

Cameron¹

1927

Archives of Disease in Childhood

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Coincidently with the rise in the amount of ketone bodies and with the corresponding fall in the alkaline reserves of the blood many observers have found a considerable fall in the percentage of blood sugar. Thus whereas in adults the blood sugar remains remarkably constant despite prolonged starvation, in children it would appear that there may be a considerable though sometimes shortlived fall and that in general the younger the child the more severe the fall. In a study of the metabolism of young children subjected to prolonged periods of fasting Shaw and Moriarty (3) found that the ketosis, the fall in the plasma bicarbonate and the hypoglyecemia were all on a much greater scale than in adult life. There was indeed a definite fall in the pH value of the blood. In the later days of the fast some degree of compensation was achieved and the sugar content became less depressed. The depletion of the glycogen reserves would appear to occur more rapidly in fasting children than in fasting adults and the body appears unable for some time to bring about a glucose synthesis sufficient to maintain a normal blood sugar.Upon children actually subject to cyclical vomiting as yet comparatively little work has been done. Hilliger (4) in 1914 first detected a fall from 0-14 to 0-07 in the blood sugar in a child with cyclical vomiting accompanying the development of the ketosis. In a young child two and a half years old, the subject of typical attacks of cyclical vomiting, Ross, Hughes and Josephs i6) found a fall in the blood sugar and of the C02 combining power of the blood, but noted that the recovery was so rapid that the hypoglyemmia could only be demonstrated during the height of the attack.

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Observations on Certain Aspects of the Cyclic Vomiting Syndrome

Dods

1935

Medical Journal of Australia

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Acetonuria in Childhood: A Study of Its Prevalency in the Medical Wards of a Children's Hospital; With an Inquiry Into Its Cause.

Cited by 3 publications

References 0 publications

A Clinical and Biochemical Study of the Subnormal Child

A Clinical and Biochemical Study of the Subnormal Child

Ketonaemia, Cyclical Vomiting and Some Nervous Disturbances in Children

Observations on Certain Aspects of the Cyclic Vomiting Syndrome

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