Acetylcholinesterase and acetylcholine receptor histochemistry on end plate regions, myotendinous junctions, and sarcolemma in the axial musculature of three teleost fish species

Mos, W.; Maslam, Suharti; Raamsdonk, W. van; Kilarski, Wincenty; Jager, S. de

doi:10.1016/s0065-1281(83)80007-5

Cited by 14 publications

(7 citation statements)

References 18 publications

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“…3,4 They reportedly are appropriate for use as general anesthetics in fish and can induce effective immobilization at low concentrations. 13,14 However, an important aspect to consider is possible species differences in the dose-dependent response regarding a more general inhibition of nerve function (anesthetic or analgesic effect) and the specific blockade of nicotinic receptors (paralytic effect) of isoeugenol, as indicated by the results reported here. Although it has not been explicitly documented that this compound causes neuromuscular blockade in fish, there is no reason to assume that the mechanism of neuromuscular transmission should be different in fish species.…”

Section: Discussionmentioning

confidence: 76%

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Effects of isoeugenol on in vitro neuromuscular blockade of rat phrenic nerve-diaphragm preparations

Ingvast-Larsson¹,

Axén²,

Kiessling³

2003

ajvr

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Isoeugenol caused a competitive blockade of neuromuscular transmission. Neostigmine restored this transmission by inhibiting acetylcholinesterase, which led to increased concentrations of acetylcholine. Because isoeugenol is used as an anesthetic in fish, further investigations are necessary to determine whether fish exposed to isoeugenol are sedated and unconscious or whether they are only paralyzed but have intact perception in afferent sensory nerves.

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Section: Discussionmentioning

confidence: 76%

“…13,14 Thus, the muscles of fish should react to substances affecting the motor end plate in a similar manner to that of muscles of other vertebrates. 13,14 Thus, the muscles of fish should react to substances affecting the motor end plate in a similar manner to that of muscles of other vertebrates.…”

Section: Discussionmentioning

confidence: 99%

Effects of isoeugenol on in vitro neuromuscular blockade of rat phrenic nerve-diaphragm preparations

Ingvast-Larsson¹,

Axén²,

Kiessling³

2003

ajvr

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“…In some teleost fish, body muscle ChE is made up exclusively of AChE [25, 26]. In contrast, body muscle from other teleosts contains both AChE and atypical PsChE [25, 27, 28].…”

Section: Discussionmentioning

confidence: 99%

Potential use of cholinesterase in monitoring low levels of organophosphates in small streams: Natural variability in three‐spined stickleback (Gasterosteus aculeatus) and relation to pollution

Sturm

Wogram

Hansen

et al. 1999

Enviro Toxic and Chemistry

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Abstract-The potential use of cholinesterase (ChE) in body muscle of three-spined stickleback (Gasterosteus aculeatus) as a biomarker of organophosphate (OP) contamination was investigated. Fish were sampled from nine headwater streams directly after the main application period (July 1995) and 2 months after the end of OP use (October 1995). Cholinesterase activity was inversely related to fish weight. Muscle ChE was comprised of both acetylcholinesterase and pseudocholinesterase. In July, fish from two sites (A and B) had significantly lower (ϳ30%) ChE activities than fish from all but one of the other sites. In October, the range of ChE activities was similar to that observed in July; however, no site significantly differed from the majority of other sites. The OP parathion was detected in suspended particulates at sites A and B. This suggests that decreased ChE in July reflects OP exposure. Because sampling of suspended particulates at site A occurred with a higher resolution than at the other sites and because decreases were close to the natural variability, however, this relationship cannot be demonstrated with certainty. The reported characteristics of ChE and its natural variability in stickleback represent baseline data for its use in the monitoring of OP contamination of small streams.

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“…1c,d). The general lack of muscle in or around the rays 2 and the lack of motor end plate-like structures 15,16 suggest that these nerves are, for the most part, sensory. While fishes are known to use fins for many forms of sensation 10,11,17 , the diversity of sensory endings and their functions has not been surveyed in detail, limiting interpretation of sensory capabilities from afferent morphology.…”

Section: Neuroanatomymentioning

confidence: 99%

The function of fin rays as proprioceptive sensors in fish

2013

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The sensation of movement and position of the limbs is critical for normal behaviours in tetrapods. In the bony fishes it is unclear what proprioceptive feedback is provided from the paired fins, the piscine homologues of the tetrapod limbs. Here we test mechanosensory abilities of afferent nerves in the pectoral fin rays, limb structures used by many fish species in propulsion and manoeuvreing. We examine the bluegill sunfish, a fish that uses its pectoral fins extensively in locomotion. We find that the activity of fin ray nerve fibres reflects the amplitude and velocity of fin ray bending. Spike sorting analyses demonstrate the presence of both slowly and rapidly adapting afferent nerve fibres. The fin sensory abilities we describe substantially expand the diversity of known vertebrate proprioceptive capabilities, and suggest that the pectoral fins need to be considered as possible proprioceptive sensors in studies of their functional morphology, movement and evolution.

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Acetylcholinesterase and acetylcholine receptor histochemistry on end plate regions, myotendinous junctions, and sarcolemma in the axial musculature of three teleost fish species

Cited by 14 publications

References 18 publications

Effects of isoeugenol on in vitro neuromuscular blockade of rat phrenic nerve-diaphragm preparations

Effects of isoeugenol on in vitro neuromuscular blockade of rat phrenic nerve-diaphragm preparations

Potential use of cholinesterase in monitoring low levels of organophosphates in small streams: Natural variability in three‐spined stickleback (Gasterosteus aculeatus) and relation to pollution

The function of fin rays as proprioceptive sensors in fish

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