Achieving equity for children and adolescents with perinatal HIV exposure: an urgent need for a paradigm shift

Mutanga, Jane Namangolwa; Ronan, Agnes; Powis, Kathleen M.

doi:10.1002/jia2.26171

Cited by 3 publications

(2 citation statements)

References 34 publications

(36 reference statements)

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“…Unfortunately, access to treatment has also been a challenge among this age category, in 2021, approximately 800,000 children living with HIV (with a range of 640,000 to 990,000) did not receive HIV treatment [10]. Although children constituted only 4% of people living with HIV, they accounted for 15% of AIDS-related deaths, and the gap in HIV treatment coverage between children and adults is widening rather than narrowing [11].…”

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confidence: 99%

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Social and Psychological Complexity Among Adolescents Living with HIV in Targeted Treatment Health Facilities in Kwara State, Nigeria – A Qualitative Study

Atibioke,

Oyasope,

Ojomo

2024

Preprint

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Background There is growing concern about the rising prevalence of HIV infection among adolescents and young people worldwide and the various challenges that accompany living with HIV among this population. This study investigated the social and psychological complexities of adolescents living with HIV in selected treatment health facilities in Kwara State, Nigeria. Methods Study adopted qualitative data collection method with six focus group discussions (FGDs) conducted across three health facilities, three sessions each for both males and females. Discussions were conducted in English and Yoruba languages, audio-recorded, transcribed, and translated into English. Content analysis was performed using MAXQDA Analytic Pro 2020. Results A total of 44 participants, comprising 24 males and 20 females aged 10 to 19, participated in the FGDs. More than ninety percent of the adolescents had not disclosed their HIV status to anyone beyond the health care providers, their parents/caregivers, and a few immediate family members. Keeping their HIV status private helped mitigate stigma and discrimination. Common immediate reactions to status disclosure to the adolescents included sadness, hopelessness, and bitterness. However, Operation Triple Zero program, which offered peer-to-peer learning and effective mental health services has been very effective and helpful. Also, sexual risk behavior is still high among sexually active adolescents despite their HIV-positive status. Conclusion Adolescents living with HIV face numerous social and psychological challenges, including sadness about their HIV-positive status. This exposes them to various mental health disorders. However, Operation Triple Zero has been acknowledged as the most effective platform for meeting their psychosocial needs.

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“…People might run away and discriminate against me if I tell them my status." [FGD 1, 14-17 years] "If I should disclose to another person aside from my family, they might broadcast my status to others" [FGD 3, 14-17 years] "I don't want to disclose my HIV status to any other person because I believe it should be kept as a secret"[FGD 4,[10][11][12][13] …”

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confidence: 99%

Social and Psychological Complexity Among Adolescents Living with HIV in Targeted Treatment Health Facilities in Kwara State, Nigeria – A Qualitative Study

Atibioke,

Oyasope,

Ojomo

2024

Preprint

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Increased risk of hospitalization among children who were HIV-exposed and uninfected compared to population controls

Brochon,

Ducruet,

Taillefer

et al. 2024

Aids

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Objectives: While studies have demonstrated increased morbidity and mortality risk in infancy among children who are HIV-exposed and uninfected (CHEU), longitudinal data are limited. The objective of this study was to assess long-term risk of hospitalization among CHEU compared to children who are HIV-unexposed and uninfected (CHUU), and determine risk factors for hospitalization among CHEU. Design: Longitudinal cohort study (1988–2015) linking the Centre maternel et infantile sur le SIDA cohort (Montreal, Quebec) to administrative data from the Régie de l’assurance maladie du Québec (RAMQ), a universal health insurance provider in the province of Quebec. Methods: CHEU from the CMIS cohort were matched 1:3 by age, sex and postal code with CHUU controls from the RAMQ database. Incidence and causes of hospitalization between CHEU and CHUU were compared using Poisson regression. Results: 726 CHEU were matched to 2178 CHUU. Risk of first hospitalization was significantly higher among CHEU at 1 year (IRR 2.22, [1.86–2.66]), 5 years (IRR 1.62, [1.39–1.90]) and over the lifespan (IRR 1.55, [1.33–1.81]). Among CHEU, significant risk factors for hospitalization on univariate regression analysis included birth year before 2005, prematurity, small for gestational age (SGA), detectable maternal viral load (dVL) at delivery, and maternal hepatitis C co-infection. In the adjusted analysis, small for gestational age and dVL remained significant risk factors. Conclusions: CHEU had a higher rate of hospitalization than CHUU controls across their lifespan. Significant risk factors included SGA and detectable maternal dVL, suggesting a need enhanced pediatric care for these children.

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Editorial: World AIDS Day 2022: putting ourselves to the test: achieving equity to end HIV

Ripamonti,

Leon

2024

Front. Public Health

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Achieving equity for children and adolescents with perinatal HIV exposure: an urgent need for a paradigm shift

Cited by 3 publications

References 34 publications

Social and Psychological Complexity Among Adolescents Living with HIV in Targeted Treatment Health Facilities in Kwara State, Nigeria – A Qualitative Study

Social and Psychological Complexity Among Adolescents Living with HIV in Targeted Treatment Health Facilities in Kwara State, Nigeria – A Qualitative Study

Increased risk of hospitalization among children who were HIV-exposed and uninfected compared to population controls

Editorial: World AIDS Day 2022: putting ourselves to the test: achieving equity to end HIV

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