2013
DOI: 10.1016/j.jdermsci.2012.11.461
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Achillea millefolium extract: an innovative anti-aging neuro-cosmetic ingredient

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“…The Achillea millefolium extract's properties for smoothing and rejuvenating skin's surface appearance were also evaluated during in vivo studies. The obtained results showed an improved expression of cytokeratin 10, transglutaminase-1, and filaggrin, and an increased epidermal thickness (+10%), cohesion, and regeneration [304,308].…”
Section: Cell Communication Supports By Stimulating Pomc-related Receptor Expressionmentioning
confidence: 85%
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“…The Achillea millefolium extract's properties for smoothing and rejuvenating skin's surface appearance were also evaluated during in vivo studies. The obtained results showed an improved expression of cytokeratin 10, transglutaminase-1, and filaggrin, and an increased epidermal thickness (+10%), cohesion, and regeneration [304,308].…”
Section: Cell Communication Supports By Stimulating Pomc-related Receptor Expressionmentioning
confidence: 85%
“…Carli et al (2016) reported that an excess of neuropeptides in the absence of receptors could induce the cells' desynchronization. For example, during aging processes in the human epidermis, when the levels of the POMC neuropeptide in the keratinocytes rise, the melanocortin receptor-2 (MC-2R) and micro-opioid receptor 1 (MOR-1)-which are the ACTH and β-endorphin receptors, respectively-decrease [100,112,304]. Hence, an imbalance of communication between the nervous and skin cells occurs [89,305].…”
Section: Cell Communication Supports By Stimulating Pomc-related Receptor Expressionmentioning
confidence: 99%