Achillea millefolium L. s.l. revisited: Recent findings confirm the traditional use

Abstract

Yarrow (Achillea millefolium L. s.l.) is traditionally used in the treatment of inflammatory and spasmodic gastro-intestinal disorders, hepato-biliary complaints and inflammation. Now we could show that the flavonoids mediated the antispasmodic properties of yarrow, whereas the dicaffeoylquinic acids caused the choleretic effects. Moreover, we observed an in vitro-inhibition of human neutrophil elastase, a protease involved in the inflammatory process, by extracts and fractions from yarrow, which suggests additional mechanisms of antiphlogistic action. The presented results confirm the traditional use of yarrow.

Antimicrobial, Antiviral Activity and GC-MS Analysis of Essential Oil Extracted from Achillea fragrantissima Plant Growing In Sinai Peninsula, Egypt

“…Ancient people had been used Achillea species in traditional medicine to alley pain, spasms and inflammation [18,3,4]. In Arabian countries all Achillea species were referred to locally names as Qaysum, Gesoom or Bu`eithraan [20,42] Numerous studies describe the various pharmacological effects of the Achillea fragrantissima hydrodistilled volatile oils in management of several diseases, used topically and orally [18][19][20][21].…”

“…Since a long period of time, plants have been a valuable source of natural products for maintaining animals and human health [2,3]. The development of multidrug-resistant(MDR) bacteria takes place because of the accumulation of different antibiotic resistance mechanisms inside the same strain which able to live in the presence of antibiotics drugs so that standard treatments become ineffective [4,[14][15][16]. Although, the pharmacological companies have produced a number of new antibiotics recently, but even then microorganism resistance to antibiotics increased throughout the world [5,7].…”

Biological activities of the hydro-alchoholic and aqueous extracts of Achillea biebersteinii Afan. (Asteraceae) grown in Jordan

“…The name Achillea refers to the Achilles in the literary Trojan War of the Iliad who used yarrow to treat the soldiers' wounds (Benedek and Kopp, 2007). deposited in the Department of Pharmaceutical Sciences, Faculty of Pharmacy, The University of Jordan.…”

Isolation of a novel piperidide from Achillea Moonshine using bioactivity guided fractionation for the treatment of acne

“…'Moonshine' was determined (Shah et al, 2015). Achillea has been traditionally used for healing wound, treat inflammation, as an antimicrobial and treat gastric and respiratory infections (Li et al, 2011;Moradi et al, 2013;Benedek and Kopp, 2007). This report was novel as this was the first time yarrow was determined to have acne treating abilities such as reducing inflammation, treating infections caused by P. acnes and S. epidermidis and removing dark pigmentation (Shah et al, 2015).…”