Achilles Tendinopathy: Evaluation, Rehabilitation, and Prevention

Rickenbach, Kristian J von; Borgstrom, Haylee; Tenforde, Adam S.; Borg‐Stein, Joanne; McInnis, Kelly C.

doi:10.1249/jsr.0000000000000855

Cited by 34 publications

(19 citation statements)

References 52 publications

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“…It endures strain and risks rupture from running, jumping, sudden acceleration or deceleration, overuse, vascular disease, neuropathy, and rheumatologic diseases, which may cause tendon degeneration. The hallmark Achilles tendon problems appear to result from tendon damage, weakness, and inelasticity ( von Rickenbach et al, 2021 ). The incidence of Achilles tendon rupture in the general population is approximately 5–10 per 100,000 ( Sheth et al, 2017 ), although it may be higher in different regions and populations; the overall incidence is increasing ( Lantto et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

Positive Association Between Fluoroquinolone Exposure and Tendon Disorders: A Nationwide Population-Based Cohort Study in Taiwan

et al. 2022

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Introduction: Fluoroquinolone exposure is reportedly associated with a higher risk of tendon disorders, tendonitis, or tendon rupture. However, studies in East Asian populations have not confirmed these risks in patients with comorbidities or concomitant medication use. This cohort study was designed to investigate the associations among fluoroquinolone exposure, comorbidities, medication use, and tendon disorders in Taiwan.Materials and Methods: This population-based, nationwide, observational, cohort study used data from the National Health Insurance Research database in Taiwan, a nationwide claims database that covers more than 99% of the Taiwanese population. The study period was from January 2000 to December 2015, and the median follow-up time was 11.05 ± 10.91 years. Patients who were exposed to fluoroquinolones for more than three consecutive days were enrolled, and patients without fluoroquinolone exposure who were matched by age, sex, and index year were enrolled as controls. The associations of comorbidities and concomitant medication use with tendon disorder occurrence were analyzed using Cox regression models.Results: The incidence of tendon disorders were 6.61 and 3.34 per 105 person-years in patients with and without fluoroquinolone exposure, respectively (adjusted hazard ratio, 1.423; 95% confidence interval [1.02,1.87]; p = 0.021). Sensitivity analyses yielded similar results. Patients under 18 and over 60 years with fluoroquinolone exposure; those with chronic kidney disease, diabetes, rheumatologic disease, cardiac disease, lipid disorder, or obesity; and those who concomitantly used statins, aromatase inhibitors, or glucocorticoids, had a significantly higher risk of tendon disorders.Conclusion: The long-term risk of tendon disorders was higher in patients with fluoroquinolone exposure than in those without fluoroquinolone exposure. Clinicians should assess the benefits and risks of fluoroquinolone use in patients at high risk of tendon disorders who require fluoroquinolone administration.

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Section: Introductionmentioning

confidence: 99%

Positive Association Between Fluoroquinolone Exposure and Tendon Disorders: A Nationwide Population-Based Cohort Study in Taiwan

et al. 2022

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“…Achilles tendinopathy (AT) is associated with overuse and is characterized by cumulative tissue microtrauma. 63 AT can be refractory to treatment given poor blood supply to the region, 1 but there has been significant recent advancement in treatment options for this pathology. 62 Accordingly, adipose-derived SVF has become a popular area of research for the treatment of AT.…”

Section: Achilles Tendinopathymentioning

confidence: 99%

Contemporary Review: The Use of Adipocyte-Derived Mesenchymal Stem Cells in Pathologies of the Foot and Ankle

Anastasio,

Bagheri,

Adams

2023

Foot & Ankle Orthopaedics

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“…The Achilles tendon is the strongest and largest tendon in the human body and is primarily responsible for plantar flexion of the ankle [28]. Achilles tendon disorders can be divided into two categories: acute ruptures and chronic overuse injuries [12].…”

Section: Introductionmentioning

confidence: 99%

Kinesiophobia contributes to worse functional and patient‐reported outcome measures in Achilles tendinopathy: a systematic review

Vivekanantha

Halai

et al. 2023

Knee surg. sports traumatol. arthrosc.

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Purpose To assess the efect of kinesiophobia or fear of reinjury on patient-reported outcome measures and physical performance measures in patients with chronic Achilles tendinopathy (AT). Methods Three databases were systematically screened for studies from inception to May 22nd, 2023 for literature investigating the impact of kinesiophobia on PROMs or physical performance metrics in AT. The authors adhered to the PRISMA and R-AMSTAR guidelines as well as the Cochrane Handbook for Systematic Reviews of Interventions. Data on demographics, pain, level of activity, self-reported injury severity, quality of life, single-leg hop performance, and heel-raise performance were recorded. Data was presented primarily in a narrative summary fashion. The MINORS score was used for all studies to perform a quality assessment of included studies. Results Six studies comprising 705 patients were included in this review. Variations of the Tampa Scale of Kinesiophobia (TSK-11 or TSK-17) were used in all studies. TSK scores were strongly correlated with the Pain Catastrophizing Score (PCS) and Visual Analogue Scale (VAS) scores and were correlated with decreased Victorian Institute of Sports Assessment Achilles (VISA-A) and Foot and Ankle Outcome Scores Quality of Life (FAOS-QoL) subscale scores. Kinesiophobia was associated with heel raise completion with conlicting evidence on correlations with hop test performance. Conclusion Increased kinesiophobia scores (> 35 points), measured by TSK are associated with worse PROMs, including increased pain, decreased quality of life, increased self-reported severity, and is also associated with poorer physical performance measures in patients with AT. Level of evidence IV.

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Achilles Tendinopathy: Evaluation, Rehabilitation, and Prevention

Cited by 34 publications

References 52 publications

Positive Association Between Fluoroquinolone Exposure and Tendon Disorders: A Nationwide Population-Based Cohort Study in Taiwan

Positive Association Between Fluoroquinolone Exposure and Tendon Disorders: A Nationwide Population-Based Cohort Study in Taiwan

Contemporary Review: The Use of Adipocyte-Derived Mesenchymal Stem Cells in Pathologies of the Foot and Ankle

Kinesiophobia contributes to worse functional and patient‐reported outcome measures in Achilles tendinopathy: a systematic review

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