Achromobacter xylosoxidans bacteremia

Manzella, John P.

doi:10.1007/bf01296150

Cited by 17 publications

(20 citation statements)

References 8 publications

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“…However, previous studies suggest that A. xylosoxidans infections are more common in immunocompromised hosts, especially those with renal insufficiency, diabetes mellitus, carcinoma, alcoholism, tuberculosis, or endogenous immunosuppression. [2, 20] Previous studies have also reported ocular infections by A. xylosoxidans in immunocompetent patients. [5, 8, 10, 12–13, 19] Cataract surgery was the only risk factor associated in the current study.…”

Section: Discussionmentioning

confidence: 99%

Endophthalmitis Caused by Achromobacter Xylosoxidans After Cataract Surgery

Villegas

Emanuelli

Flynn

et al. 2014

Retina

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Purpose To report Achromobacter xylosoxidans as a cause of both acute-onset and delayed-onset postoperative endophthalmitis after cataract surgery. Methods A non-comparative, consecutive case series of patients with culture-proven A. xylosoxidans endophthalmitis between 1970 and 2012. Cataract surgery and intraocular lens placement were performed in all patients prior to endophthalmitis. Positive cultures were obtained from the vitreous, capsular bag, and/or the removed intraocular lens. Results The clinical diagnosis was confirmed in 4 patients with positive cultures. Two endophthalmitis patients had a preliminary culture report of Pseudomonas species. In addition to receiving intravitreal antibiotics, all patients underwent capsulectomy and intraocular lens removal at the time of pars plana vitrectomy. Visual acuity at last follow up was 20/40 or better in 2 of 4 (50%) but the remaining 2 patients were 20/200 or worse. Conclusion A. xylosoxidans may be a cause of acute, recurrent, and delayed-onset postoperative endophthalmitis after cataract surgery. Complete capsulectomy and intraocular lens removal can be considered in recurrent and recalcitrant patients.

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Section: Discussionmentioning

confidence: 99%

Endophthalmitis Caused by Achromobacter Xylosoxidans After Cataract Surgery

Villegas

Emanuelli

Flynn

et al. 2014

Retina

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“…It is often encountered in aqueous environments but rarely recognized as a human pathogen. Despite its low intrinsic pathogenicity, it can cause serious infections in humans, especially immunocompromised hosts [8, 11, 12]. A. xylosoxidans has been reported in patients with cancer, neutropenia, bone marrow or liver transplant, diabetes mellitus, renal failure, cystic fibrosis, HIV infection, IgM deficiency, neonates, and healthy individuals [2–4, 5–8, 10, 11, 13, 15–17].…”

Section: Discussionmentioning

confidence: 99%

“…Despite its low intrinsic pathogenicity, it can cause serious infections in humans, especially immunocompromised hosts [8, 11, 12]. A. xylosoxidans has been reported in patients with cancer, neutropenia, bone marrow or liver transplant, diabetes mellitus, renal failure, cystic fibrosis, HIV infection, IgM deficiency, neonates, and healthy individuals [2–4, 5–8, 10, 11, 13, 15–17]. The clinical manifestation of infection caused by A. xylosoxidans is variable and includes primary bacteremia, pneumonia, meningitis, endocarditis, cholecystitis, peritonitis, pyelonephritis, osteomyelitis, lymphadenitis and keratitis [3–6, 8, 14, and 18].…”

Section: Discussionmentioning

confidence: 99%

Complicated Septic Shock Caused by Achromobacter Xylosoxidans Bacteremia in a Patient with Acute Lymphoblastic Leukemia

Al-Jasser¹,

Al-Anazi²

2007

Libyan J Med

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“…Until now, infection with A. x. xylosoxidans had been reported in only two patients with hematological disor ders (acute myelogenous leukemia [24], and Hodgkin's disease [25]). Both patients died in the bacteremia course.…”

Section: Patientsmentioning

confidence: 99%

Infection by <i>Alcaligenes xylosoxidans</i> subsp. <i>xylosoxidans</i> in Neutropenic Patients

Knippschild¹,

Schmid²,

Uppenkamp

et al. 1996

Oncology

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Alcaligenes xylosoxidans subsp. xylosoxidans (A. x. xylosoxidans) is a nonfer-menting gram-negative peritrichous rod and opportunistic pathogen. The organism is frequently found in an aqueous environment. In the past few years, nosocomial infections caused by A. x. xylosoxidans have become more evident. The literature suggests that systemic infections are severe and often lethal and an optimal antibiotic therapy is not well established. This report describes nosocomial infections in 11 patients of a hematology ward over a 2-month period. Primary infection occurred during the neutropenic phase after cytotoxic chemotherapy. Reinfection spread from central venous catheters that had been implanted before the first infection. The bacteremia was successfully treated by imipenem. None of the 11 patients died from the bacteremia, but 3 died of their underlying diseases. Despite an intensive search for the source, the route of infection remained uncertain. Nosocomial infections by A. x. xylosoxidans are of growing importance in high-risk patients. Although the source of infection often remains unknown, infection seems to originate from contaminated solutions. Treatment with imipenem and the removal of central venous catheter systems successfully eliminated A. x. xylosoxidans, which adheres to plastic material.

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Achromobacter xylosoxidans bacteremia

Cited by 17 publications

References 8 publications

Endophthalmitis Caused by Achromobacter Xylosoxidans After Cataract Surgery

Endophthalmitis Caused by Achromobacter Xylosoxidans After Cataract Surgery

Complicated Septic Shock Caused by Achromobacter Xylosoxidans Bacteremia in a Patient with Acute Lymphoblastic Leukemia

Infection by <i>Alcaligenes xylosoxidans</i> subsp. <i>xylosoxidans</i> in Neutropenic Patients

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