In the present study, an investigation of the effect of using acetic acid (CH 3 COOH) in condenser descaling on the exhaust emissions and the performance of Assiut Thermal Power Plant. Efficient condenser operation maintains turbine efficiency; benefits consumers by reducing the amount of emissions. Condenser vacuum has a great effect on the unit efficiency to a degree that it reduces the generated load by 112 MW (35.9%) in unit one of Assiut Power Plant and to the extent that cleaning became very necessary. From environmentally point of view an organic, biodegradable, locally produced, effective and cheap de-scaling agent was the very applicable one and this meet with acetic acid. Actually, condenser cleaning leads to an improvement in the turbine efficiency and raises the maximum load generated from the unit (from 200 MW before cleaning to 290 MW after cleaning), decreases fuel consumed for MW (from 249 kg/MWh at load 200 MW to 220 kg/MWh at load 290 MW), reduces the overall fuel consumption, consequently, reduces emissions as CO, CO 2 , SO x , NO x , ground level ozone, PM, VOC, ashes, solid deposits, haze, thermal pollution, and reduces contribution to global warming, heat island effect at Assiut city. In brief, the condenser cleaning process reduces the environmental pollution from the unit which in turn minimizes the health impact of these pollutants.