Acid-triggeredin vivoaggregation of Janus nanoparticles for enhanced imaging-guided photothermal therapy

Abstract

The poor tumor delivery efficiency remains a significant challenge for the integrated nanoplatform for diagnosis and treatment. Nanotherapeutics capable of aggregation in response to the tumor microenvironment has received considerable...

Tumor versus Tumor Cell Targeting in Metal-Based Nanoparticles for Cancer Theranostics

“…This variation in diameter enhanced the MRI contrast capability, PTT efficiency, and PAI performance of the functionalized mNPs. The versatility of these mNPs could help better localize the primary tumor mass and improve its treatment [87].…”

Enhancing MRI through high loading of superparamagnetic nanogels with high sensitivity to the tumor environment

“… 27 Furthermore, the T 2 value can be significantly enhanced by achieving high loading or concentration of magnetic nanoparticles in the tumor region. 28 Therefore, it is highly desirable to employ magnetic nanoparticles with a high magnetic moment and saturation magnetization, as they exhibit rapid response to an external magnetic field. However, the strong magnetic attraction between magnetosome particles can lead to aggregation and precipitation in water as well as biological fluid environments.…”

Boosting Carrier–Phonon Scattering in Cu2–xS Nanochains for 90.5% Photothermal Conversion Efficiency in Near-Infrared II Region

“…Plasmonic nanocrystals present the enhanced optical properties associated with localized surface plasmon resonance (LSPR). − More interestingly, the excitation plasmon can be efficiently converted to heat via carrier relaxation (i.e., carrier–phonon and phonon–phonon scattering). − After thermal dissipation, plasmonic nanocrystals have been used to heat up the local environment. The effective local heating ability has resulted in many practical applications, including photothermal therapeutics, − photothermal catalysis, − and steam generation. , …”