Acid triterpenes and flavonoids from Baccharis ligustrina (Asteraceae)

Moreira, Francisco P.M; Branco, Alexsandro; Pizzolatti, Moacir Geraldo; Morais, Anselmo A.; Monachè, Franco Delle

doi:10.1016/s0305-1978(02)00149-7

Cited by 7 publications

(4 citation statements)

References 4 publications

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“…Spectral data (IR, 1 H NMR and 13 C NMR) for isolated compounds was compared and were according with those published, and the structures were confirmed by on-column high-temperature gas chromatography sing a DB-1HT fused silica capillary column (15 m length × 0.25 mm ID × 0.1 mm film; Agilent Technologies, Santa Clara, CA, USA). The oven temperature was increased from 80 to 70 • C at a rate of 10 • C min −1 , with the flame ionization detector (FID) temperature set at 380 • C and co-elution with standards obtained as previously described (Moreira et al, 2003;Meotti et al, 2006). The kaurenoic acid compound was obtained from Baccharis illinita flowers and was isolated and characterized as previously described by Verdi et al (2004).…”

Section: Extraction and Isolationmentioning

confidence: 99%

Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation

Boller

Soldi

Marques

et al. 2010

Journal of Ethnopharmacology

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Section: Extraction and Isolationmentioning

confidence: 99%

Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation

Boller

Soldi

Marques

et al. 2010

Journal of Ethnopharmacology

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“…25 Oleanolic acid ( Figure 7) was also isolated from B. rufescens, 24 and Baccharis ligustrina D.C., which also yielded ursolic acid. 26 H O H COOH…”

Section: Triterpenoidsmentioning

confidence: 99%

“…25 The flavonoids naringenin and hispidulin were also isolated from B. ligustrina. 26 Examples of other flavonoids isolated from the Baccharis genus also included eight known flavonoids from B. gaudichaudiana, 17 and the species B. rufescens, which yielded the flavonoids cirsimaritin (5,4'-dihydroxy-6,7-dimethoxyflavone) and cirsiliol (5,3',4'trihydroxy-6,7-dimethoxyflavone). 24…”

Section: Flavonoidsmentioning

confidence: 99%

Baccharis (Compositae): a review update

Abad¹,

Bermejo²

2006

Arkivoc

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The Baccharis genus is an important source of natural medicinal products. The information collected here is an attempt to cover the most recent developments in the ethnopharmacology, pharmacology and phytochemistry of this genus. This review describes its traditional and folkloric uses, phyto-constituents and pharmacological and toxicological reports of the prominent species of the genus Baccharis. Flavonoids and other phenolic compounds, diterpenoids and volatile constituents have been reported as the major phyto-constituents of the Baccharis species. Pharmacological studies are mainly based on the anti-inflammatory, antioxidant, antimicrobial and antifungal properties. The potential for development of leads from Baccharis genus continues to grow. The information summarized here is intended to serve as a reference tool to practitioners in the fields of ethnopharmacology and chemistry of natural products.

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“…Our previous study on the flower extracts resulted in the isolation of twelve flavonoids and three kaurene diterpenoids [2]. As a continuation of our investigations into the chemical constituents of the genus Baccharis [3,4], we now report the occurrence of a further eleven flavonoids, a kaurane diterpene and a few coumaric and caffeic esters of the stem and leaves of B. illinita. Given that this plant has high flavonoid concentrations and that phenolic substances, mainly the flavonoids, have given good results in relation to tests for vascular activity [5], we screened for anticoagulant and platelet activity.…”

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confidence: 53%

Anticoagulant effect and Constituents of Baccharis illinita

Pizzolatti

Verdi

Brighente

et al. 2006

Natural Product Communications

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Chemical investigation of ethanolic extracts of the leaves and stems of Baccharis illinita resulted in the isolation and identification of retusin, quercetin-3, 7, 4'-trimethyl ether, aromadendrin-7-methyl ether, 3-(4-hydroxyphenyl)-2-propenoic acid (E and Z) hexacosyl ester, 3-(3, 4-dihydroxyphenyl)-2-propenoic acid (E) hexacosyl ester and hexacosanoyl acid acetyl ester (all new for this genus), together with apigenin-7, 4'-dimethyl ether, kaempferol-3, 7, 4'-trimethyl ether, kaempferol-7,4'dimethyl ether, p-coumaric acid, hexacosanol, and stigmasta-5, 22-dien-3-ol (3β, 22E, 24S) hexadecanoyl. Their structures were assigned by comparison of the obtained spectroscopic data with those in the literature. Extracts of the flowers, roots and stems demonstrated marked anticoagulant activity, but only the extract of the stems had any significant effect on platelet aggregation.

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Acid triterpenes and flavonoids from Baccharis ligustrina (Asteraceae)

Cited by 7 publications

References 4 publications

Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation

Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation

Baccharis (Compositae): a review update

Anticoagulant effect and Constituents of Baccharis illinita

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