Acide gamma-hydroxy-butyrique (GHB) : plus qu’un agent de soumission chimique, une véritable source d’addiction

Poppers dependence: The mask behind hypersexuality

“…In 1990, a French decree forbade the sale or the free distribution of products containing butyl or pentyl nitrites or their isomers. [13,14] when treating hypersexual disorder. propyl, isopropyl, cyclohexyl) became available on the market.…”

“…Le tabagisme occupe une part prédominante dans la physiopathologie de ces évènements pour son rôle sur les plaquettes et au niveau de l'endothélium vasculaire ; et il est régulièrement présent dans les SCA du sujet jeune [3,4]. Effectivement plusieurs publications font état de l'absence de récidive dans 85 à 96 % des cas [1,3,5,14]. Le pronostic de ces patients apparaît relativement favorable par rapport aux porteurs de lésions d'athérome.…”

Risk assessment of GBL as a substitute for the illicit drug GHB in the Netherlands. A comparison of the risks of GBL versus GHB

“…To avoid prosecution, pure GBL (99.9%) on the Internet is sold as a cleaning agent, wheel cleaner and paint remover with the explicit warning of the seller that the product is not intended for human consumption (Veenker, 2011). In France, GBL is available as a solvent or paint stripper in specialty stores and on the Internet (Karila et al, 2009). Remarkably, at the time GBL was not yet classified as an illegal drug in the UK 66.2% of the 225 seized GHB samples, which were offered in London nightclubs, contained GBL rather than GHB (Wood et al, 2008).…”

Anion exchange SPE and liquid chromatography–tandem mass spectrometry in GHB analysis

“…This drug also induces short-term anterograde amnesia, and increases libido; undoubtedly contributing to the use of GHB in drug facilitated crimes (DFC [5,6]). GHB is alleged to increase growth hormone excretion [7], it also has been abused by bodybuilders as an alternative to steroids [8]. Because of its powerful effects on psychomotor performance, GHB also severely impairs driving ability [9].…”