Acidic degradation and enhanced antioxidant activities of exopolysaccharides from Cordyceps sinensis mycelial culture

Chemical composition and free radical scavenging activities of a sulphated polysaccharide extracted from abalone gonad (Haliotis Discus Hannai Ino)

“…It is widely reported that natural polysaccharides and theirs derivatives extracted from plant and fungus possess antioxidant activities (Chen, Zhang, Qu, & Xie, 2008;Chen, Zhang, & Xie, 2005;Kuda & Ikemori, 2009;Yan et al, 2009). However, there has been no report about antioxidant polysaccharide of animal origin except for our previous research (Zhu et al, 2008).…”

Use ofOphiocordyceps sinensis(syn.Cordyceps sinensis) combined with angiotensin-converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) versus ACEI/ARB alone in the treatment of diabetic kidney disease: a meta-analysis

“…91 In vitro and in vivo studies have proved that a polysaccharide isolated from O. sinensis and containing glucose, mannose, and galactose exhibited strong antioxidant activity, acted as a direct free-radical scavenger, and might have attenuate renal failure. 92,93 The aqueous extract of the Indian species of Ophiocordyceps sinensis has spectacular antioxidant and anti-inflammatory capabilities. 94 In addition, the melanin derived from O. sinensis also exhibited chelating ability and antioxidant activity.…”

Antihyperglycemic activity of Ophiocordyceps sinensis: A Review

“…Yan et al (2009) reported the antioxidant polysaccharides designated EPS-1 with an average MW of 38 kDa was hydrolyzed in diluted sulfuric acid solution at pH 1 and 90°C to yield two major MW fractions: 3.0 kDa and 30 kDa possessed high about 30-80% of antioxidant and radicalscavenging activities. Wang et al (2009) also reported the antioxidant polysaccharide was found to be a glucomannogalactan with a monosaccharide composed of glucose, mannose, and galactose in a ratio of 2.8:2.9:1, and its total carbohydrate content and average MW were 99.0% and 8.1 kDa, respectively.…”

“…Leung et al (2009) indicated that polysaccharides obtained from O. sinensis with MW ranging from 5 to 210 kDa has antioxidant and hypoglycemic activities. From review literatures that Chen et al, 2008;Hui Polysaccharides et al, 2006;Li et al, 2001;Li et al, 2003;Wang et al, .2009;Wu et al, 2005;Yan et al, 2009;Zhang et al, 2003;Zhong et al, 2009Hypoglycemic Balon et al, 2002El Ashry et al, 2012;Polysaccharides Guo et al, 2010;Guo et al, 2011;Huang et al, 2002;Kan et al, 2012;Kiho et al, 1993;Li et al, 2006;Lo et al, 2004;Lo et al, 2006;Wang et al, 2003;Zhong et al, 2009 regarding the bioactive ingredients and bioactivities in antidiabetic and antioxidant effects of O. sinensis are shown in Table 1.…”