Ácido Hipocloroso: una Nueva Alternativa como Agente Antimicrobiano y para la Proliferación Celular para Uso en Odontología

Lafaurie, Gloria Inés; Calderón, Justo Leonardo; Zaror, Carlos; Millan, Lina V; Castillo, Diana Marcela

doi:10.4067/s0718-381x2015000300019

Cited by 11 publications

(6 citation statements)

References 24 publications

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“…Sodium hypochlorite oral rinse constitutes an important new development in periodontal and peri‐implant self‐care, and most likely also in caries prevention . Oral rinsing twice‐weekly for 3 months with 0.25% sodium hypochlorite (sourced from Clorox ® Regular Bleach; The Clorox Company, Oakland, CA, USA), together with conventional oral hygiene, yielded improvements of 94% in plaque‐free facial surfaces, 195% in plaque‐free lingual surfaces and 421% in the number of teeth showing no bleeding on probing; the same clinical variables improved by 29‐30% in control subjects .…”

Section: Patient Self‐carementioning

confidence: 99%

Periodontitis: facts, fallacies and the future

Slots¹

2017

Periodontology 2000

754

531

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This volume of Periodontology 2000 represents the 25th anniversary of the Journal, and uses the occasion to assess important advancements in periodontology over the past quarter-century as well as the hurdles that remain. Periodontitis is defined by pathologic loss of the periodontal ligament and alveolar bone. The disease involves complex dynamic interactions among active herpesviruses, specific bacterial pathogens and destructive immune responses. Periodontal diagnostics is currently based on clinical rather than etiologic criteria, and provides limited therapeutic guidance. Periodontal causative treatment consists of scaling, antiseptic rinses and occasionally systemic antibiotics, and surgical intervention has been de-emphasized, except perhaps for the most advanced types of periodontitis. Plastic surgical therapy includes soft-tissue grafting to cover exposed root surfaces and bone grafting to provide support for implants. Dental implants are used to replace severely diseased or missing teeth, but implant overuse is of concern. The utility of laser treatment for periodontitis remains unresolved. Host modulation and risk-factor modification therapies may benefit select patient groups. Patient self-care is a critical part of periodontal health care, and twice-weekly oral rinsing with 0.10-0.25% sodium hypochlorite constitutes a valuable adjunct to conventional anti-plaque and anti-gingivitis treatments. A link between periodontal herpesviruses and systemic diseases is a strong biological plausibility. In summary, research during the past 25 years has significantly changed our concepts of periodontitis pathobiology and has produced more-effective and less-costly therapeutic options.

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Section: Patient Self‐carementioning

confidence: 99%

Periodontitis: facts, fallacies and the future

Slots¹

2017

Periodontology 2000

754

531

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“…Hypochlorous acid (HClO) is electrically neutral, while hypochlorite ions (ClO-) are electrically negative. These ions constitute free chlorine, which, when in contact with bacteria, oxidizes them in a process known as chemical disinfection (Lafaurie et al, 2015).…”

Section: How Does Chlorine Destroy Bacteria?mentioning

confidence: 99%

“…El ácido hipocloroso (HClO) es eléctricamente neutro y los iones hipoclorito (ClO -) son eléctricamente negativos. Estos iones forman cloro libre que al estar en contacto con las bacterias las oxidan, a este proceso se le conoce como desinfección química (Lafaurie et al, 2015).…”

Section: How Does Chlorine Destroy Bacteria?unclassified

Chlorine and its importance in the inactivation of bacteria, can it inactivate viruses?

Muñoz-Castellanos¹,

Borrego-Loya²,

Villalba-Bejarano³

et al. 2021

RMF

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Sodium hypochlorite (NaClO) and its active ingredient, hypochlorous acid (HClO), are the most widely used chlorine-based disinfectants. HClO is a fast-acting antimicrobial that interacts with many biomolecules, including amino acids, lipids, nucleic acids, and sulfur containing membrane components, causing cell damage. In this review, we present examples of the effectiveness of chlorine in general disinfection procedures to inactivate bacteria and, under some conditions, bacteria in biofilms and viruses.

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“…hongos- (Lafaurie et al, 2015). Ninguno de los medicamentos anteriormente descritos son dióxido de cloro, sino compuestos diferentes, aunque tengan como base de su composición al cloro, por lo que no serían tomados en cuenta como evidencia del uso medicinal del dióxido de cloro.…”

Section: Revista Humanista| 45unclassified

¿El dióxido de cloro podría ser la panacea universal?

Bejarano¹

2021

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El dióxido de cloro es una sustancia química descubierta en 1914, desde entonces su principal uso fue potabilizar el agua. A inicios de 2020, en la primera ola de la pandemia causada por el SARS-CoV-2, se promocionó esta sustancia como una panacea universal sin tomar en cuenta la diferente fisiopatología de cada enfermedad. A falta de un tratamiento eficaz contra el SARS-CoV-2 muchas personas empezaron a consumirlo como tratamiento, generando varios efectos secundarios desde quemaduras en esófago hasta la muerte. Haciendo una revisión de los artículos científicos disponibles se pudo comprobar que no existe evidencia para el uso de dióxido de cloro para ninguna enfermedad, pero sí como desinfectante de superficies.

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Ácido Hipocloroso: una Nueva Alternativa como Agente Antimicrobiano y para la Proliferación Celular para Uso en Odontología

Cited by 11 publications

References 24 publications

Periodontitis: facts, fallacies and the future

Periodontitis: facts, fallacies and the future

Chlorine and its importance in the inactivation of bacteria, can it inactivate viruses?

¿El dióxido de cloro podría ser la panacea universal?

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