Acinar Cell Cystadenoma (Acinar Cystic Transformation) of the Pancreas: the Radiologic-Pathologic Features

Abstract

Acinar cystic transformation of the pancreas is also known as acinar cell cystadenoma (ACC), and this is an extremely rare benign lesion that was first described in April 2002. We report here on a case of a previously asymptomatic patient with pancreatic ACC and this was diagnosed by computed tomography (CT) and magnetic resonance imaging (MRI). To the best of our knowledge, there is no previous report concerning the CT or MRI features of ACC in the medical literature. We present here the CT, MRI and pathological findings of pancreatic ACC.

The Easter Egg: Acinar Cell Cystadenoma Raffaele Pezzilli

“…From a clinical point of view, the tumor has been reported mainly in females and the age of diagnosis ranges from 39 to 66 years [3]. The most frequent clinical presentation is acute pancreatitis, but asymptomatic cases, have been reported [3].…”

“…The most frequent clinical presentation is acute pancreatitis, but asymptomatic cases, have been reported [3]. The tumor is frequently localized in the head, and multiple localizations in the pancreas have also been reported [3].…”

“…The most frequent clinical presentation is acute pancreatitis, but asymptomatic cases, have been reported [3]. The tumor is frequently localized in the head, and multiple localizations in the pancreas have also been reported [3]. The cysts may be uni-or multilocular and a capsule may sometimes be present [3]; size ranges from 0.1 to 10 cm [3].…”

“…The tumor is frequently localized in the head, and multiple localizations in the pancreas have also been reported [3]. The cysts may be uni-or multilocular and a capsule may sometimes be present [3]; size ranges from 0.1 to 10 cm [3]. Ultrasound-guided aspiration of the cystic fluid may be helpful in cases with pancreatic cystic lesions; the levels of amylase are elevated in the cystic fluid of pseudocysts whereas the carcinoembryonic antigen levels may be elevated in mucinous cystic tumors and keratinous and amorphous debris can be found in lymphoepithelial cysts.…”

“…Acinar cell cystadenoma (also called cystic acinar transformation) is a rare pancreatic neoplasm which was described for the first time in 2002 [1]; it is one of the acinar cell tumors of the pancreas, which also include acinar cell cystadenocarcinomas and acinar cell carcinomas [2,3].…”