ÖzetGiriş ve Amaç: Özellikle yoğun bakım ünitelerinde hastane enfeksiyonlarına neden olan Acinetobacter baumannii Gramnegatif, nonfermentatif bir kokobasildir. Birçok antibiyotiğe direnç geliştirmesi nedeniyle tedavisi zordur. Direnç profilleri hastanelere göre değiştiği için tedavide uygun antibiyotik protokolünü belirlemek amacıyla bu tür bakterilerin direnç paternlerini bilmek önemlidir. Bu çalışmanın amacı, hastanemizde çeşitli klinik örneklerinden izole edilen A. baumannii suşlarının antibiyotik direnç oranlarının belirlenmesidir.
AbstractIntroduction: Acinetobacter baumannii is a Gram-negative, nonfermentative coccobacillus causes nosocomial infections especially in intensive care units. It is difficult to treat due to it has developed resistance to many antibiotics. As the resistance profiles vary according to hospitals, it is important to know the resistance patterns of such bacteria in order to determine the appropriate antibiotic protocol in the treatment. The aim of this study was to determine the antibiotic resistance of A. baumannii strains isolated from various clinical specimens in our hospital. Methods: Antibiotic resistance of A.baumannii strains isolated from various clinical samples between 2011-2013 years in Microbiology Laboratory of Konya Numune Hospital were evaluated retrospectively. The identification of isolates and antibiotic susceptibility tests were performed by Vitek 2 Compact (bioMérieux, France ) automated system. Results: In this study: 275 A. baumannii strains were isolated from 136 bronchial aspiration fluid, 41 sputum, 37 blood, 32 urine and 29 wound samples. All isolates were susceptible to colistin. The antibiotic resistance rates of the strains were 38.9% for amikacin, 64.0 % for gentamicin, 88.4% for ampicillinsulbactam, 89.5 % for imipenem and meropenem, 90.5 % for ceftazidime, 93.1 % for cefepime, 94.2 % for levofloxacin, 94.5 % for piperacillin-tazobactam and ciprofloxacin.