Acinic cell carcinoma, papillary-cystic variant of the parotid gland: A case report with review of literature

Acinic Cell Carcinoma-Papillary Cystic Variant with numerous psammoma body: A Case Report

“…However, a mucinous background with large, mucin-filled cells and intermediate cells is an important clue to the diagnosis of MEC. On the other hand, the presence of papillary growth nature and neoplastic cells lacking intracellular mucin, absence of intermediate cells, characteristically seen in papillary-cystic variant, they tend to form "hobnail cells", presumably after releasing their secretions into glandular spaces [10] , are features in favoring a diagnosis of ACC-PCV. In contrast, MEC requires empirical lymph node dissection, and hence this distinction has clinical correlation [9] .…”

Acinic cell carcinoma, papillary-cystic variant: a rare case diagnosed in fine needle aspiration cytology

“…2 Acinic Cell Carcinoma is the third most common malignant tumor of parotid after the muco-epidermoid and adenoid cystic carcinoma. 3,4 Acinic Cell Carcinoma in children is very rare, since it represents about the 3% of all malignant parotid neoplasm. 2 Acinic Cell Carcinoma constitute 17% of primary salivary gland tumor.…”

“…Acinic Cell Carcinoma is a malignant epithelial neoplasm arising from pleuripotent stem cells. 3,4 It is slowly growing tumor with female preponderance most commonly occur during fifth and sixth decades of life. 5,6 Possible causes of acinic cell carcinoma include previous radiation exposure and familial predisposition.…”

“…solid, solid-lobular, acinar-microcystic, papillary cystic, tubuloductal, follicular/macrocystic and dedifferentiated. 4 The cytological picture often is dominated by cells denoted as acinic cells because of their great resemblance to normal acinar cells. We are presenting a case of an acinic cell carcinoma, papillarycystic variant in a 9-year-old female.…”

Acinic Cell Carcinoma of the Parotid Gland: A Case Report and Review of the Literature

“…They are composed of diverse cell types and include acinic cells, vacuolated cells, intercalated cells, nonspecific glandular cells and clear cells. Large lobules or nests of tumor cells with little intervening stroma are characteristics [ 9 , 10 , 11 ]. The histologic grading of acinic cell carcinomas is controversial, and unlike clinical staging, histomorphology has not proven to be reliable in predicting its behavior [ 12 ].…”