Acknowledgments

Moore, Keith L.; Persaud, Vid; Torchia, Mark G.

doi:10.1016/b978-1-4377-2001-3.00027-7

Cited by 12 publications

(15 citation statements)

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“…The placenta is a unique organ of fetal origin that provides nutrients and oxygen to the developing fetus and also serves as the avenue for carbon dioxide and other fetal waste products to be eliminated via the maternal circulation [14]. The placenta starts to develop soon after blastocyst implantation.…”

Section: Placental Structure and Functionmentioning

confidence: 99%

Placental control of drug delivery

Al-Enazy

Ali

Albekairi

et al. 2017

Advanced Drug Delivery Reviews

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The placenta serves as the interface between the maternal and fetal circulations and regulates the transfer of oxygen, nutrients, and waste products. When exogenous substances are present in the maternal bloodstream—whether from environmental contact, occupational exposure, medication, or drug abuse—the extent to which this exposure affects the fetus is determined by transport and biotransformation processes in the placental barrier. Advances in drug delivery strategies are expected to improve the treatment of maternal and fetal diseases encountered during pregnancy.

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Section: Placental Structure and Functionmentioning

confidence: 99%

Placental control of drug delivery

Al-Enazy

Ali

Albekairi

et al. 2017

Advanced Drug Delivery Reviews

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“…Congenital uterine anomalies result from abnormal formation, fusion or resorption of the Müllerian ducts during fetal life (Moore et al ., 2008). These anomalies have been associated with an increased rate of miscarriage, preterm delivery and other adverse fetal outcomes (Green and Harris, 1976; Rock and Schlaff, 1985; Acien, 1993; Raga et al ., 1997; Grimbizis et al ., 2001; Tomazevic et al ., 2007).…”

Section: Introductionmentioning

confidence: 99%

The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review

Chan¹,

Jayaprakasan²,

Zamora³

et al. 2011

Human Reproduction Update

621

372

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BACKGROUNDThe prevalence of congenital uterine anomalies in high-risk women is unclear, as several different diagnostic approaches have been applied to different groups of patients. This review aims to evaluate the prevalence of such anomalies in unselected populations and in women with infertility, including those undergoing IVF treatment, women with a history of miscarriage, women with infertility and recurrent miscarriage combined, and women with a history of preterm delivery.METHODSSearches of MEDLINE, EMBASE, Web of Science and the Cochrane register were performed. Study selection and data extraction were conducted independently by two reviewers. Studies were grouped into those that used ‘optimal’ and ‘suboptimal’ tests for uterine anomalies. Meta-analyses were performed to establish the prevalence of uterine anomalies and their subtypes within the various populations.RESULTSWe identified 94 observational studies comprising 89 861 women. The prevalence of uterine anomalies diagnosed by optimal tests was 5.5% [95% confidence interval (CI), 3.5–8.5] in the unselected population, 8.0% (95% CI, 5.3–12) in infertile women, 13.3% (95% CI, 8.9–20.0) in those with a history of miscarriage and 24.5% (95% CI, 18.3–32.8) in those with miscarriage and infertility. Arcuate uterus is most common in the unselected population (3.9%; 95% CI, 2.1–7.1), and its prevalence is not increased in high-risk groups. In contrast, septate uterus is the most common anomaly in high-risk populations.CONCLUSIONSWomen with a history of miscarriage or miscarriage and infertility have higher prevalence of congenital uterine anomalies compared with the unselected population.

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“…Prenatal exposure to a toxic drug can disrupt the development of many systems necessary for life. For instance, prenatal PM 2.5 exposure may hinder the development of the cardiovascular and central nervous systems [ 38 ]. Furthermore, prenatal PM 2.5 exposure may disrupt lung maturation by interacting with lung growth, neurogenesis, and differentiation [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

Future Health Risk Assessment of Exposure to PM2.5 in Different Age Groups of Children in Northern Thailand

Amnuaylojaroen

Parasin

2023

Toxics

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Particulate matter with a diameter less than 2.5 (PM2.5) is one of the major threats posed by air pollution to human health. It penetrates the respiratory system, particularly the lungs. In northern Thailand, the PM2.5 concentrations have significantly increased in the past decade, becoming a major concern for the health of children. This study aimed to assess the health risk of PM2.5 in different age groups of children in northern Thailand between 2020 and 2029. Based on the PM2.5 data from the simulation of the Nested Regional Climate Model with Chemistry (NRCM-Chem), the hazard quotient (HQ) was used to estimate the possible risk from PM2.5 exposure in children. In general, all age groups of children in northern Thailand will tend to experience the threat of PM2.5 in the future. In the context of age-related development periods, infants are at a higher risk than other groups (toddlers, young children, school age and adolescents), but adolescents also have a lower risk of exposure to PM2.5, albeit maintaining a high HQ value (>1). Moreover, the analysis of risk assessment in different age groups of children revealed that PM2.5 exposure might indeed affect adolescent risk differently depending on gender, with males generally at a heightened risk than females in adolescence.

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Acknowledgments

Cited by 12 publications

References 0 publications

Placental control of drug delivery

Placental control of drug delivery

The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review

Future Health Risk Assessment of Exposure to PM2.5 in Different Age Groups of Children in Northern Thailand

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