Acne arising on a facial Becker nevus following the lines of Blaschko

Hayashida, Marina Zoéga; Enokihara, Mílvia Maria Simões e Silva; Hikawa, Renato Shintani; Cestari, Silmara da Costa Pereira

doi:10.1590/abd1806-4841.20176588

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…The significant role of these drugs in the effectiveness of treatment cannot be verified by the previous pieces of evidence presented in this report. Nevertheless, given that immune cells, such as dermal melanophage may be present in the lesion, a correlation between the immune system alteration and the exacerbation of this lesion may exist (11); therefore, the immune deficiency caused by these immunosuppressive drugs can contribute to the healing of the lesion and the favorable response to laser therapy (without any recurrence). Iyidal et al (12) described a patient who had both vitiligo and Becker's nevus at the same time; however, Becker's nevus had developed ten years after the onset of vitiligo.…”

Section: Discussionmentioning

confidence: 99%

Becker’s Nevus in a 24-Year-Old Female Patient with Rheumatoid Arthritis: A Case Report of a Laser Therapy Without Recurrence

et al. 2020

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Introduction: Becker's nevus is a type of cutaneous hamartoma that occurs as a brown hyperpigmented patch with irregular borders. The exact pathogenesis of Becker's nevus is not clear, but hormonal disturbances might play a triggering role. Q-switched lasers have demonstrated favorable effects on improving hyperpigmentation lesions; however, following using a Q-switched laser, the nevus usually reoccurs. Case Presentation: In this study, we described a 24-year-old female patient with Becker's nevus treated with Q-switched ruby laser (694 nm) whose lesion recovered without any complications or recurrence. The patient had rheumatoid arthritis and has been taking oral methotrexate, hydroxychloroquine, and prednisolone for ten years. Conclusions: Although hyperpigmentation has reported following laser therapy, our patient did not develop any pigmentation, and the lesion did not recur, which can be due to her concurrent drugs, suggesting the role of the immune system in recurrence of Backer's nevus.

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Section: Discussionmentioning

confidence: 99%

Becker’s Nevus in a 24-Year-Old Female Patient with Rheumatoid Arthritis: A Case Report of a Laser Therapy Without Recurrence

et al. 2020

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“…However, it can occasionally occur as multiple or bilateral lesions on any parts of the body, less than 5% in areas considered unusual such as the, face, abdomen, upper arm and elbow, as the case in our patients. Becker's nevus, predominately seen in men,is an androgen-dependent lesion because it becomes more prominent after puberty [1]. Cilnicaly this nevus usually as a circumscribed, hyperpigmented patch with irregular outline that gradually enlarges with associated hypertrichosis, usually develops after the hyperpigmentation, and the hairs become coarser and darker with time [2].…”

Section: Discussionmentioning

confidence: 99%

Atypical location of Becker’s nevus: About two cases. Clinical and dermoscopic features

Elharrouni¹,

Douhi²,

Mrabat³

et al. 2020

Our Dermatol Online

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“…Facial involvement is relatively rare but might give rise to a considerable cosmetic concern [ 6 ]. Recurrent acne and eczema in the affected areas were occasionally reported [ 7 , 8 ]. Becker’s nevus syndrome (BNS) refers to conditions in which generalized BN is associated with developmental anomalies, including unilateral breast hypoplasia and other cutaneous, muscular, and skeletal defects.…”

Section: Introductionmentioning

confidence: 99%

ACTB Mutations Analysis and Genotype–Phenotype Correlation in Becker’s Nevus

2021

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Becker’s nevus (BN) is a cutaneous hamartoma which is characterized by circumscribed hyperpigmentation with hypertrichosis. Recent studies have revealed that BN patients harbored postzygotic ACTB mutations, which were restricted to arrector pili muscle lineage. We screened for ACTB mutations in 20 Chinese patients with BN and found that recurrent mutations (c.C439A or c.C439T) in ACTB were detected in the majority of BN patients. However, more than 20% of the patients were negative for ACTB mutations, suggesting a possible genetic heterogeneity in Becker’s nevus. Interestingly, these mutations were also detected in dermal tissues outside the arrector pili muscle. We further performed genotype–phenotype correlation analysis, which revealed that lesions above the waistline, including the trunk above the anterior superior spine level, upper limbs and face, or covering more than 1% BSA were more likely to be positive for ACTB mutations. Altogether, our results provide further evidence of postzygotic ACTB mutations in BN patients and suggest a possible genotype–phenotype correlation of BN.

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Acne arising on a facial Becker nevus following the lines of Blaschko

Cited by 4 publications

References 5 publications

Becker’s Nevus in a 24-Year-Old Female Patient with Rheumatoid Arthritis: A Case Report of a Laser Therapy Without Recurrence

Becker’s Nevus in a 24-Year-Old Female Patient with Rheumatoid Arthritis: A Case Report of a Laser Therapy Without Recurrence

Atypical location of Becker’s nevus: About two cases. Clinical and dermoscopic features

ACTB Mutations Analysis and Genotype–Phenotype Correlation in Becker’s Nevus

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