Acne e dieta: verdade ou mito?

Abstract

Numerous studies were published over the last 50 years to investigate whether diet is associated with the etiology of acne. Although older studies well known by dermatologists that refute the association between acne and diet exist, their scientific foundation is weak. New articles have recently brought to light evidence contrary to previous findings. Therefore, we would like to investigate whether diet, directly or indirectly, influences one or more of the four fundamental etiopathogenic pillars of acne: (1) hyperproliferation of basal keratinocytes, (2) increase of sebaceous production, (3) colonization by Propionibacterium acnes, and (4) inflammation. Keywords: Acne vulgaris; Diet; Glycemic index Resumo: Nos últimos 50 anos, foram publicados inúmeros estudos com a finalidade de comprovar se a dieta está relacionada à etiologia da acne. Embora existam estudos antigos, que são bem difundidos entre os dermatologistas e negam a associação entre acne e dieta, seu delineamento científico é pobre. Recentemente, novos artigos demonstraram evidências contrárias às publicações anteriores. Sendo assim, os autores realizaram esta revisão bibliográfica com o intuito de averiguar se a dieta influencia direta ou indiretamente um ou mais dos quatro pilares etiopatogênicos fundamentais da acne: (1) hiperproliferação dos queratinócitos basais, (2) aumento da produção sebácea, (3) colonização pelo Propionibacterium acnes e (4) inflamação.

Dissatisfaction and acne vulgaris in male adolescents and associated factors

“…2,13-20 Lack of confidence, social withdrawal, feelings of insecurity and inferiority, limited employment opportunities, difficulties at work and in interpersonal relationships, and suicidal ideation are also related to the effects of changes in individuals with acne. 2,5,6,10,16 …”

Incidence of acne vulgaris in young adult users of protein-calorie supplements in the city of João Pessoa - PB

“…12,18 Hyperinsulinemia plays a role in circulating concentration of IGF-1 and the growth factor binding protein similar to insulin-3 (IGFBP-3), which act directly on the proliferation of keratinocytes and apoptosis. IGF-1 seems to mediate comedogenic factors, like androgens, growth hormone and glucocorticoids.…”

Types of Acne and Associated Therapy: A Review

“…2,4,8,9 Many authors say that the diet doesn't influence the appearance of acne and that such a statement is nothing but a myth. However, Costa et al (2010), based on various literature reviews, said the not westernized people do not suffer from acne, because their food doesn't include processed foods, such as dairy products, refined sugars and oils. Smith et al also found, in a clinical trial, in which a group was exposed to a diet with low glycemic load (GL) and a control group to a diet with high GL, that after 12 weeks, the group with low diet GL presented a significant reduction in the number of acne lesions.…”

“…Smith et al also found, in a clinical trial, in which a group was exposed to a diet with low glycemic load (GL) and a control group to a diet with high GL, that after 12 weeks, the group with low diet GL presented a significant reduction in the number of acne lesions. 2,4,10,11 Although the diagnosis of acne is a relatively easy rule, the various forms may require a differential diagnosis.…”