“…8,[11][12][13] The late lesions of AKN, with draining sinuses and large, keloidal masses, are often refractory to treatment, including therapy with topical and intralesional steroids, 5,8,12 topical and oral antibiotics, retinoids, 10,16 and irradiation. 5,6,10,14,17 Surgical approaches to late-stage AKN include epilation, 5,8,12,14 excision with second-intention healing, 10,13,16 excision with primary closure, 5,14,16,18 and excision with grafting. 5,12,14,16,17,19 The purpose of this study was to determine the efficacy of excision with primary closure in the treatment of 25 patients with extensive and refractory AKN.…”