Acne Vulgaris: Its Aetiology and Treatment

Belisario, John C.

doi:10.1111/j.1440-0960.1951.tb01410.x

Cited by 22 publications

(13 citation statements)

References 38 publications

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“…We also examined other food items such as soda, french fries, pizza, and chocolate candy, some of which had been hypothesized to be associated with acne. 2,8 Nutrient intakes were computed by multiplying the frequency of consumption of each unit of food and the nutrient content of the specified portions based on the nutrient values in foods obtained from US Department of Agriculture sources and food manufacturers, and then summing the contributions from all foods. 11 These were energy-adjusted by using the residuals from the regression of nutrient intake on total caloric intake.…”

Section: Study Populationmentioning

confidence: 99%

“…1 There are also significant social and emotional costs. 2 Although acne affects all ages in Western countries, prevalence starts to increase from the age of 4 years, and peaks at 16 to 18 years when 75% to 98% of the population is affected. 3 Acne results from hyperkeratinization and obstruction of the pilosebaceous follicles secondary to androgen-stimulated failure of normal desquamation of the follicular epithelium, androgen-stimulated sebum production, colonization of the follicles by Propionibacterium acne, and, variably, inflammation.…”

mentioning

confidence: 99%

“…In addition, we examined other foods, such as french fries, pizza, and chocolate candy that have been hypothesized to be associated with teenage acne. 1,2 The study was approved by the Institutional Review Boards of the Brigham and Women's Hospital and the Harvard School of Public Health.…”

mentioning

confidence: 99%

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High school dietary dairy intake and teenage acne

Adebamowo

Spiegelman

Danby

et al. 2005

Journal of the American Academy of Dermatology

248

188

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Section: Study Populationmentioning

confidence: 99%

mentioning

confidence: 99%

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High school dietary dairy intake and teenage acne

Adebamowo

Spiegelman

Danby

et al. 2005

Journal of the American Academy of Dermatology

248

188

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“…A review of the literature in 1951 indicated that dietary factors, especially chocolate, had a significant influence on the exacerbation of acne [Belisario, 1951]. This idea has fallen from favor in recent times, mostly based on a blinded study sponsered by the Chocolate Manufacturers Association of the USA [Fulton et al, 1969;Chan and Rohr, 2001].…”

Section: Acne and Psychosomatic Or Other Trigger Factorsmentioning

confidence: 99%

Acne Is Not a Trivial Disease! Psychosomatic Aspects in Routine Therapy

Niemeier¹,

Kupfer²,

Gieler³

2002

Dermatol Psychosom

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Patients with acne may develop psychological problems as a consequence of their condition – often independent of the severity of their skin condition. Emotional problems due to the disease should be taken seriously and included in the treatment plan. A purely dermatological therapy may not achieve its purpose. Even mild to moderate disease can be associated with significant depression and suicidal ideation, and psychologic change does not necessarily correlate with disease severity. Acne patients suffer particularly under social limitations and reduced quality of life. Psychic comorbidities in acne are probably greater than generally assumed. Attention should be paid to psychosomatic aspects especially if there is suspicion of depressive-anxious disorders, particularly with evidence of suicidal tendencies, body dysmorphic disorders, or also of disrupted compliance. Therefore, patients who report particularly high emotional distress or dysmorphic tendencies due to the disease should be treated adequately, if possible, by interdisciplinary therapy. The dermatologist must have some knowledge of the basics of psychotherapy and psychopharmacology, which sometimes must be coupled with systemic and topical treatments of acne in conjunction with socalled psychosomatic basic treatment.

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“…In the 1930s, acne was considered to be a disease of disturbed carbohydrate metabolism because early work suggested that impaired glucose tolerance occurred in acne patients (4). On the basis of these observations and the anecdotal impressions of physicians, patients were often discouraged from eating excessive amounts of carbohydrates and high-sugar foods (5,6). The diet and acne connection finally fell from favor in 1969 when a clinical study found no exacerbation of acne lesions in a group that ingested a chocolate bar compared with a group that ingested a placebo bar (7).…”

Section: Introductionmentioning

confidence: 99%

A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial

Smith

Mann

Braue

et al. 2007

The American Journal of Clinical Nutrition

242

178

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Background: Although the pathogenesis of acne is currently unknown, recent epidemiologic studies of non-Westernized populations suggest that dietary factors, including the glycemic load, may be involved. Objective: The objective was to determine whether a low-glycemicload diet improves acne lesion counts in young males. Design: Forty-three male acne patients aged 15-25 y were recruited for a 12-wk, parallel design, dietary intervention incorporating investigator-blinded dermatology assessments. The experimental treatment was a low-glycemic-load diet composed of 25% energy from protein and 45% from low-glycemic-index carbohydrates. In contrast, the control situation emphasized carbohydrate-dense foods without reference to the glycemic index. Acne lesion counts and severity were assessed during monthly visits, and insulin sensitivity (using the homeostasis model assessment) was measured at baseline and 12 wk. Results: At 12 wk, mean (ȀSEM) total lesion counts had decreased more (P ҃ 0.03) in the low-glycemic-load group (Ҁ23.5 Ȁ 3.9) than in the control group (Ҁ12.0 Ȁ 3.5). The experimental diet also resulted in a greater reduction in weight (Ҁ2.9 Ȁ 0.8 compared with 0.5 Ȁ 0.3 kg; P 0.001) and body mass index (in kg/m 2 ; Ҁ0.92 Ȁ 0.25 compared with 0.01 Ȁ 0.11; P ҃ 0.001) and a greater improvement in insulin sensitivity (Ҁ0.22 Ȁ 0.12 compared with 0.47 Ȁ 0.31; P ҃ 0.026) than did the control diet. Conclusion: The improvement in acne and insulin sensitivity after a low-glycemic-load diet suggests that nutrition-related lifestyle factors may play a role in the pathogenesis of acne. However, further studies are needed to isolate the independent effects of weight loss and dietary intervention and to further elucidate the underlying pathophysiologic mechanisms.Am J Clin Nutr 2007;86: 107-15.

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Acne Vulgaris: Its Aetiology and Treatment

Cited by 22 publications

References 38 publications

High school dietary dairy intake and teenage acne

High school dietary dairy intake and teenage acne

Acne Is Not a Trivial Disease! Psychosomatic Aspects in Routine Therapy

A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial

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