2017
DOI: 10.3390/ma10121426
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Acoustic Anomalies and Fast Relaxation Dynamics of Amorphous Progesterone as Revealed by Brillouin Light Scattering

Abstract: The amorphous state of pharmaceuticals has attracted much attention due to its high bioavailability and other advantages. The stability of the amorphous state in relation with the local molecular mobility is important from both fundamental and practical points of view. The acoustic properties of amorphous progesterone, one of the representative steroid hormones, were investigated by using a Brillouin inelastic light scattering technique. The Brillouin spectrum of the longitudinal acoustic mode exhibited distin… Show more

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“…One of the experimental methods to investigate elastic properties is Brillouin spectroscopy, which probes the frequency and attenuation (damping) of acoustic waves in the gigahertz range [29]. The strains caused by high-frequency acoustic waves can be coupled to fast dynamics in condensed matters.…”
Section: Introductionmentioning
confidence: 99%
“…One of the experimental methods to investigate elastic properties is Brillouin spectroscopy, which probes the frequency and attenuation (damping) of acoustic waves in the gigahertz range [29]. The strains caused by high-frequency acoustic waves can be coupled to fast dynamics in condensed matters.…”
Section: Introductionmentioning
confidence: 99%