Acoustic Funnel and Buncher for Nanoparticle Injection

Li, Zheng; Shi, Lei; Cao, Lushuai; Liu, Zhengyou; Küpper, Jochen

doi:10.1103/physrevapplied.11.064036

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…Fig. 3 shows calculated cooling rates using the full model (11) and the approximation for small velocities (12) for the change in energy. Up to relative velocities of 100 m/s the calculated cooling rate does not strongly depend on velocity and the approximation of small velocities is applicable.…”

Section: B Comparison To Newton's Law Of Coolingmentioning

confidence: 99%

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Microscopic force for aerosol transport

Roth,

Amin,

Samanta

et al. 2020

Preprint

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A key ingredient for single particle diffractive imaging experiments is the successful and efficient delivery of sample. Current sample-delivery methods are based on aerosol injectors in which the samples are driven by fluid-dynamic forces. These are typically simulated using Stokes' drag forces and for micrometer-size or smaller particles, the Cunningham correction factor is applied. This is not only unsatisfactory, but even using a temperature dependent formulation it fails at cryogenic temperatures. Here we propose the use of a direct computation of the force, based on Epstein's formulation, that allows for high relative velocities of the particles to the gas and also for internal particle temperatures that differ from the gas temperature. The new force reproduces Stokes' drag force for conditions known to be well described by Stokes' drag. Furthermore, it shows excellent agreement to experiments at 4 K, confirming the improved descriptive power of simulations over a wide temperature range.

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Section: B Comparison To Newton's Law Of Coolingmentioning

confidence: 99%

“…There aerosolized nanoparticles were transported into a cryogenically-cooled heliumfilled buffer-gas cell, where the nanoparticles were rapidly cooled [10]. The low temperature reduces particle losses and broadening of the stream due to diffusion, and it allows for better subsequent nanoparticle control [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Microscopic force for aerosol transport

Roth,

Amin,

Samanta

et al. 2020

Preprint

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“…strongly align and orient the particles in the laboratory frame [20,21], or to produce very high densities through the focusing of the particles with external fields [22,23].…”

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confidence: 99%

Controlled beams of shock-frozen, isolated, biological and artificial nanoparticles

Samanta

Amin

Estillore

et al. 2020

Structural Dynamics

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X-ray free-electron lasers (XFELs) promise the diffractive imaging of single molecules and nanoparticles with atomic spatial resolution. This relies on the averaging of millions of diffraction patterns off identical particles, which should ideally be isolated in the gas phase and shockfrozen in their native structure. Here, we demonstrated that polystyrene nanospheres and Cydia pomonella granulovirus can be transferred into the gas phase, isolated, and very quickly shockfrozen, i. e., cooled to 4 K within microseconds in a helium-buffer-gas cell, much faster than state-of-the-art approaches. Nanoparticle beams emerging from the cell were characterised using particle-localisation microscopy with light-sheet illumination, which allowed for the full reconstruction of the particle beams, focused to < 100 µm, as well as for the determination of particle flux and number density. The experimental results were quantitatively reproduced and rationalised through particle-trajectory simulations. We propose an optimised setup with cooling rates for few-nanometers particles on nanoseconds timescales. The produced beams of shockfrozen isolated nanoparticles provide a breakthrough in sample delivery, e. g., for diffractive imaging and microscopy or low-temperature nanoscience.

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