Acoustic Neurinoma in a Child : A Case Report

Anegawa, Shigetaka; Hayashi, Takashi; Torigoe, R; Iwaisako, Kosuke; Sakae, Norimasa

doi:10.7887/jcns.7.315

Jpn J Neurosurg

1998

DOI: 10.7887/jcns.7.315

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Acoustic Neurinoma in a Child : A Case Report

Shigetaka Anegawa¹,

Takashi Hayashi²,

R Torigoe³

et al.

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2000

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Pediatric acoustic schwannoma showing rapid regrowth with high proliferative activity

Harada¹,

Nishizaki²,

Adachi³

et al. 2000

Child's Nervous System

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Acoustic schwannoma is a slow-growing tumor and usually occurs in adult patients. We report a rare pediatric case of acoustic schwannoma with high proliferative potential. A 10-year-old boy was diagnosed as having a right cerebellopontine angle tumor. The tumor was subtotally resected. Histological examination revealed a typical acoustic schwannoma with a few mitotic figures. Chromosomal analysis showed no abnormality on the long arm of chromosome 22 associated with neurofibromatosis type 2. The lesion re-grew rapidly as an acoustic schwannoma, necessitating subtotal resection on three occasions and CyberKnife radiosurgery. The immunohistochemical MIB-1 staining indices of the specimens obtained at the first, second, and third operations were 2.3%, 4.6% and 14.7%, respectively. The immunohistochemical proliferative potential of acoustic schwannoma is discussed.

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Pediatric acoustic schwannoma showing rapid regrowth with high proliferative activity

Harada¹,

Nishizaki²,

Adachi³

et al. 2000

Child's Nervous System

View full text Add to dashboard Cite

show abstract

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Acoustic Neurinoma in a Child : A Case Report

Cited by 1 publication

References 13 publications

Pediatric acoustic schwannoma showing rapid regrowth with high proliferative activity

Pediatric acoustic schwannoma showing rapid regrowth with high proliferative activity

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