Acquired childhood aphasia as a consequence of COVID‐19 and its differential diagnosis from speech–language pathologist perspective: A case study

Fameen, Ridha; K, Rinsha Pravin; Pooja, S; Rashmi, V; Bhattarai, Biraj; Abhishek, B P

doi:10.1002/ccr3.6587

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Adolescent age groups (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) years were more likely to test positive for COVID-19 infections compared to younger children. This agrees with what was reported in a study conducted in Bauchi State, North-East Nigeria, where 81.1% of the patients were adolescents and fell within the age group of 15-19 years [26] and had seroprevalence comparable to adults in some studies [27].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, even with a mild clinical course, children may suffer long-term symptoms following the infection, significantly affecting their quality of life; a condition described by the WHO using the term “post COVID-19 condition”, and generally known as “long COVID” [ 13 ]. Long-term post-discharge psychological and mental health outcomes have been reported among children previously admitted with COVID-19 infection [ 14 ]; high risk for anxiety and depression was found among children even with mild COVID-19 infection [ 15 ]; and developmental manifestations have also been reported [ 13 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

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Epidemiology of COVID-19 among Children and Adolescents in Sudan 2020–2021

Khairy,

Elhussein,

Elbadri

et al. 2023

Epidemiologia

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Children and adolescents account for a small proportion of confirmed COVID-19 cases, with mild and self-limiting clinical manifestations. The distribution and determinants of COVID-19 among this group in Sudan are unclear. This study used national COVID-19 surveillance data to study the epidemiology of COVID-19 among children and adolescents in Sudan during 2020–2021. A cross-sectional study was performed to estimate the reported incidence of children and adolescents with COVID-19; the clinical features; and the mortality among those who tested positive for COVID-19. A total of 3150 suspected cases of COVID-19 infection fulfilled the study criteria. The majority of cases were above 10 years of age, 52% (1635) were males, and 56% (1765) were asymptomatic. The reported incidence rates of COVID-19 among children and adolescents in Sudan was 1.3 per 10,000 in 2021. Fever, cough, and headache were the most frequent symptoms reported among the suspected cases. The case fatality rate was 0.2%. Binary logistic regression revealed that loss of smell was the most significantly associated symptom with a positive test. We recommend further study to identify risk factors. Additionally, we recommend including these age groups in the vaccination strategy in Sudan.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Epidemiology of COVID-19 among Children and Adolescents in Sudan 2020–2021

Khairy,

Elhussein,

Elbadri

et al. 2023

Epidemiologia

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COVID-19 susceptibility, hospitalization and severity and the risk of brain cortical structure: a Mendelian randomization study

Sun,

Shi,

Chen

et al. 2024

QJM: An International Journal of Medicine

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Background Observational studies have reported structural changes in the brains of patients with coronavirus disease 2019 (COVID-19); it remains unclear whether these associations are causal. Aim We evaluated the causal effects of COVID-19 susceptibility, hospitalization and severity on cortical structures. Design Mendelian randomization (MR) study. Methods Data on the different COVID-19 phenotypes were obtained from the latest large-scale genome-wide association study (R7) of the COVID-19 Host Genetics Initiative. Brain structure data, including cortical thickness (TH) and surface area (SA), were obtained from the ENIGMA Consortium. Additionally, we employed the round 5 dataset released in January 2021 as the validation cohort. The inverse-variance weighted (IVW) method was used as the primary analysis in MR. Sensitivity analyses were conducted to evaluate heterogeneity and pleiotropy. We performed enrichment analysis on the MR analyses that passed the sensitivity analysis filtering. Results After IVW and sensitivity analyses, we observed causal associations between COVID-19 susceptibility and rostral middle frontal SAw (P = 0.0308, β = −39.1236), cuneus THw (P = 0.0170, β = −0.0121), medial orbitofrontal THw (P = 0.0002, β = 0.0225), postcentral THw (P = 0.0217, β = −0.0106), temporal pole THw (P = 0.0077, β = 0.0359), medial orbitofrontal SAnw (P = 0.0106, β = −24.0397), medial orbitofrontal THnw (P = 0.0007, β = 0.0232), paracentral SAnw (P = 0.0483, β = −20.1442), rostral middle frontal SAnw (P = 0.0368, β = −81.9719) and temporal pole THnw (P = 0.0429, β = 0.0353). COVID-19 hospitalization had causal effects on medial orbitofrontal THw (P = 0.0053, β = 0.0063), postcentral THw (P = 0.0143, β = −0.0042), entorhinal THnw (P = 0.0142, β = 0.0142), medial orbitofrontal THnw (P = 0.0147, β = 0.0065) and paracentral SAnw (P = 0.0119, β = −7.9970). COVID-19 severity had causal effects on rostral middle frontal SAw (P = 0.0122, β = −11.8296), medial orbitofrontal THw (P = 0.0155, β = 0.0038), superior parietal THw (P = 0.0291, β = −0.0021), lingual SAnw (P = 0.0202, β = −11.5270), medial orbitofrontal THnw (P = 0.0290, β = 0.0039), paracentral SAnw (P = 0.0180, β = −5.7744) and pars triangularis SAnw (P = 0.0151, β = −5.4520). Conclusion Our MR results demonstrate a causal relationship between different COVID-19 phenotypes and cortical structures.

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Acquired childhood aphasia as a consequence of COVID‐19 and its differential diagnosis from speech–language pathologist perspective: A case study

Cited by 2 publications

References 17 publications

Epidemiology of COVID-19 among Children and Adolescents in Sudan 2020–2021

Epidemiology of COVID-19 among Children and Adolescents in Sudan 2020–2021

COVID-19 susceptibility, hospitalization and severity and the risk of brain cortical structure: a Mendelian randomization study

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