Acquired premature ejaculation and male accessory gland infection: relevance of ultrasound examination

Vignera, Sandro La; Condorelli, Rosita A.; Vicari, Enzo; Favilla, Vincenzo; Morgia, Giuseppe; Calogero, Aldo E.

doi:10.4103/1008-682x.155539

Cited by 12 publications

(7 citation statements)

References 20 publications

(23 reference statements)

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“…A recent study demonstrated that in patients with male accessory gland infection (MAGI), patients with PE showed a mean value of the SVs APD detected before ejaculation, which was significantly higher compared to those without PE. 29 These results here represented the higher mean APD of SV in the patients with PE compared to healthy volunteers and confirmed that the peculiar ultrasound phenotype of SV may be associated with PE. In addition, these results revealed a positive linear relationship between PEDT score and the APD of SV, which was consistent with their results despite the difference in the correlation coefficient.…”

Section: Discussionsupporting

confidence: 84%

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Relation of size of seminal vesicles on ultrasound to premature ejaculation

Hong

Feng

et al. 2017

Asian J Androl

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Myriad biological factors have been proposed to explain premature ejaculation (PE). However, data correlating PE with seminal vesicles (SVs) are sparse. The study aimed to evaluate the relationship between the size of SV and PE. The cross-sectional study included 44 outpatients with PE and 44 volunteers without PE, and the size of SV was compared. Self-estimated intravaginal ejaculatory latency time, the Premature Ejaculation Diagnostic Tool (PEDT), the International Index of Erectile Function-15, and the National Institutes of Health-Chronic Prostatitis Symptom Index were used for assessment of symptoms. Compared to the control group, the PE group had significantly higher mean anterior-posterior diameter (APD) of SV (P < 0.001). The optimal mean APD of SV cutoff level was 9.25 mm for PE. In the PE group, PEDT was also higher with a mean APD of SV ≥9.25 mm compared with mean APD of SV <9.25 mm. PEDT was significantly correlated with the mean APD of SV (r = 0.326, P = 0.031). The seminal plasma proteins were compared between six PE and six matched control cases by mass spectrometry and it was shown that 102 proteins were at least 1.5-fold up- or down-regulated. Among them, GGT1, LAMC1, and APP were significantly higher in the PE group. These results indicated that men with a larger mean APD of SV might have a higher PEDT score. Transrectal ultrasound of SV should be considered in the evaluation of patients with premature ejaculation. SV might be a potential target for the treatment of patients with PE and ultrasound change in SV.

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Section: Discussionsupporting

confidence: 84%

“…In addition, these results revealed a positive linear relationship between PEDT score and the APD of SV, which was consistent with their results despite the difference in the correlation coefficient. 29 Thus, the ultrasound change in SV is possibly associated with PE.…”

Section: Discussionmentioning

confidence: 99%

Relation of size of seminal vesicles on ultrasound to premature ejaculation

Hong

Feng

et al. 2017

Asian J Androl

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“…These forms differently impact sperm quality, sometimes irreversibly [19]. They also may contribute to sexual dysfunction, such premature ejaculation [31].…”

Section: Discussionmentioning

confidence: 99%

The Risky Health Behaviours of Male Adolescents in the Southern Italian Region: Implications for Sexual and Reproductive Disease

Perri

Lofaro

Izzo

et al. 2019

JCM

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Recent epidemiological studies suggest an increase of sexual and reproductive chronic diseases caused by problematic behaviours acquired during peri-pubertal age. The aims of our study were: (i) to investigate awareness of sexual transmitted infections (STIs) among adolescents; (ii) to describe the close relationship between possibly incorrect lifestyles during adolescence and reproductive and sexual disturbances during adulthood. The “Amico-Andrologo” survey is a permanent nationwide surveillance program supported by the Italian Ministry of Health. We administered a validated structured interview to investigate the lifestyle of adolescents and their knowledge of STIs. We selected a cohort of 360 male high-school students aged ≥18 years old. In this cohort, 150 (41.5%) were smokers while 59 (19.7%) smoked more than 10 cigarettes/day; 25 (9.3%) declared a consumption ≥6 drinks/weekend; and 65 (19.7%) were habitual cannabis consumers (at least twice/week). Among the sample of students selected, the main sources of sexual disease information were the internet and friends. The perceived level of knowledge on STIs was the same between students that used contraceptive methods and students that did not. The present results demonstrate that adolescents in Calabria do not receive appropriate information about risky health behaviours. Therefore, there is a necessity for specific educational programs to increase awareness of dangerous behaviours during the transitional age that is relevant for a safe sexual and reproductive adult life.

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“…The clinical presentation of patients with MAGI (male accessory gland inflammation) could be very heterogeneous; in fact, these patients may require andrological evaluation for problems (male infertility) [ 1 , 2 ] and/or symptoms (chronic pelvic pain, ejaculatory and urinary disorders, and sexual dysfunction) [ 3 ]. Previously, we have shown that in the clinical practice, the use of a specific questionnaire [SI-MAGI (Structured Interview about Male Accessory Gland Inflammation)] helps to discriminate the differential diagnosis [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Chronic Administration of Tadalafil Improves the Symptoms of Patients with Amicrobic MAGI: An Open Study

Vignera

Condorelli

Mongioì

et al. 2017

International Journal of Endocrinology

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Aim of this study was to evaluate the effects of pharmacological treatment with Tadalafil 5 mg daily on symptoms and quality of sperm parameters in selected patients with amicrobic MAGI (male accessory gland inflammation). 120 patients with amicrobic MAGI (mean age 27.0 ± 6.0 years) with mild-moderate ED (erectile dysfunction) according to IIEF-5 (International Index of Erectile Function 5 Items) scores underwent pharmacological treatment with Tadalafil 5 mg daily for six months. Before and after treatment these patients were evaluated through IIEF-5, semen analysis (according to WHO Criteria, 2010), SI-MAGI (Structured Interview about Male Accessory Gland Inflammation), and ultrasound evaluation. Patients with PVE (prostate-vesciculo-epididymitis) showed a significant increase in the percentage of spermatozoa with total (16.0 ± 8.0 versus 30.0 ± 6.0%) and progressive motility (8.00 ± 10.0 versus 25.0 ± 6.00%). It was a significant reduction of the number of patients with complicated ultrasound forms (30.0 versus 52.0) and a significant increase of the number of patients with uncomplicated ultrasound form (90.0 versus 68.0). Finally, there was a significant reduction in the percentage of patients with alterations of sexual function different from DE, such as premature ejaculation (4.00 versus 8.00%), painful ejaculation (4.00 versus 10.0%), delayed ejaculation (12.50 versus 8.00%), and decreased libido (10.0 versus 25.0%).

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Acquired premature ejaculation and male accessory gland infection: relevance of ultrasound examination

Cited by 12 publications

References 20 publications

Relation of size of seminal vesicles on ultrasound to premature ejaculation

Relation of size of seminal vesicles on ultrasound to premature ejaculation

The Risky Health Behaviours of Male Adolescents in the Southern Italian Region: Implications for Sexual and Reproductive Disease

Chronic Administration of Tadalafil Improves the Symptoms of Patients with Amicrobic MAGI: An Open Study

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