Acquisition of chemiluminescence spectral profiles using a continuous flow manifold with two dimensional CCD detection

Segura‐Carretero, Antonio; Fernandez, Julio Rodriguez; Worsfold, Paul J.

doi:10.1039/a910301p

Cited by 16 publications

(12 citation statements)

References 12 publications

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“…Other papers employ intensity vs wavelength registers obtained from special devices (DDC) in order to determine an analyte [15,16] We validated our findings with a reference material …”

Section: Discussionsupporting

confidence: 69%

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Multivariate calibration applied to simultaneous chemiluminescence determination of cobalt and chromium

et al. 2002

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The simultaneous determination of chromium and cobalt in water samples has been studied. Chemiluminescence registers based on the luminol-hydrogen peroxide reaction have obtained by a batch procedure. PLS algorithms have employed to model the time-response (formation and destruction of emitter). The influence of the presence of two metals and the non-linearity relationship between response and concentration have been evaluated in the signal. Different experimental designs and the selection of variables have been tested. The calibration set has been selected based on two criteria: unicomponent and/or bicomponent standard solutions and the slope calculated from linear univariate calibration. The response has been modelled providing high percentages of explained variance, robust models and low prediction errors. The proposed methodology has been validated using test standard solutions and a standard reference material of fresh water. Accurate results have proved the advantages of this method for the simultaneous determination of chromium and cobalt in water samples.

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“…Other papers employ intensity vs wavelength registers obtained from special devices (DDC) in order to determine an analyte [15,16] We validated our findings with a reference material …”

Section: Discussionsupporting

confidence: 69%

“…The simultaneous determination is achieved using wavelength discrimination or mathematical resolution [15,16]. The use of two different reactions have described for Co and Fe determination in the same manifold [17].…”

Section: Introductionmentioning

confidence: 99%

Multivariate calibration applied to simultaneous chemiluminescence determination of cobalt and chromium

et al. 2002

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“…The average absolute difference between the standard deviation calculated by equation (3) and the actual one was only about 0.7 counts over the spectral range 450-850 nm and the counts range 10-4000.…”

Section: Intrinsic Uncertainties Of Count Measurementsmentioning

confidence: 79%

“…Owing to their compact size, rigid structure, the absence of moving parts and ability to provide practically simultaneous optical measurements over a wide range of wavelengths, these devices are particularly suitable for automated analytical systems. Typical applications include flow injection systems based on spectrophotometric detection [1,2] and chemiluminescence measurements [3,4]. A universal microflow analyser based on sequential and bead injection 'lab-on-valve' using a CCD spectrometer for absorbance and fluorescence measurements has also been described [5].…”

Section: Introductionmentioning

confidence: 99%

Monte Carlo simulation for the prediction of precision of absorbance measurements with a miniature CCD spectrometer

Tsaousoglou

Bolis²,

Efstathiou³

2003

Journal of Analytical Methods in Chemistry

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The precision characteristics of the absorbance measurements obtained with a low-cost miniature spectrometer incorporating an array detector were evaluated. Uncertainties in absorbance measurements were due to a combination of non-uniform light intensity and detector response over the wavelength range examined (350-850 nm), in conjunction with the digitization of the intensity indications and the intrinsic noise of the detecting elements. The precision characteristics are presented as contour plots displaying the expected RSD% of absorbances on the absorbance versus wavelength plane. The minimum RSD% for the spectrometer configuration tested was observed within the 0.2-1.5 absorbance units and 500-750 nm wavelength range. Without invoking signal enhancement features of the data-acquisition program (scan average, higher integration times, smoothing based on averaging the signal detected by adjacent pixels), the attainable precision within this range was 0.4-0.8%. A computer program based on Monte Carlo simulations was developed for the prediction of absorbance precision characteristics under various conditions of measurements.

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“…Moreover, CL emission intensities are sensitive to a variety of environmental factors such as temperature, solvent, ionic strength, pH and other species present in the system . Several techniques have been suggested to increase the specificity of CL analysis; such as using masking agents , chromatography and wavelength discrimination . In recent years, we have used a time‐resolved CL approach to reduce the effect of interference from cysteine, citric acid and ascorbic acid in plasma samples .…”

Section: Introductionmentioning

confidence: 99%

Multiway analysis applied to time‐resolved chemiluminescence for simultaneous determination of paracetamol and codeine in pharmaceuticals

et al. 2016

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This method is based on the enhancing effect of codeine (COD) and paracetamol (PAR) on the chemiluminescence (CL) reaction of Ru(phen)3 (2+) with Ce(IV). In the batch mode, COD gives a relatively sharp peak with the highest CL intensity at 4.0 s, whereas the maximum CL intensity of the PAR appears at ~60 s after injection of Ce(IV) solution. Whole CL time profiles allowed use of the time-resolved CL data in combination with multiway calibration techniques, as multiway partial least squares (N-PLS), for the quantitative determination of both COD and PAR in binary mixtures. In this work, we found that the impact of Ce(IV) concentration on the CL intensity was different for COD and PAR. Therefore, a Ce(IV) concentration mode was added to the time and sample modes to obtain 3D data. The percent relative standard deviation (%RSD) values for 10 determinations of 1.0 × 10(-5) mol/L of COD and 1.0 × 10(-4) mol/L of PAR were 6.1% and 8.7%, respectively. The limit of detection (LOD) values (S/N = 3) were 0.9 × 10(-8) mol/L and 1.0 × 10(-6) mol/L for COD and PAR, respectively. The proposed method was successfully applied to the determination of PAR and COD in commercial pharmaceutical formulations. Acceptable recoveries (90-110%) were obtained for the quantification of these drugs in the real samples. Copyright © 2016 John Wiley & Sons, Ltd.

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Acquisition of chemiluminescence spectral profiles using a continuous flow manifold with two dimensional CCD detection

Cited by 16 publications

References 12 publications

Multivariate calibration applied to simultaneous chemiluminescence determination of cobalt and chromium

Multivariate calibration applied to simultaneous chemiluminescence determination of cobalt and chromium

Monte Carlo simulation for the prediction of precision of absorbance measurements with a miniature CCD spectrometer

Multiway analysis applied to time‐resolved chemiluminescence for simultaneous determination of paracetamol and codeine in pharmaceuticals

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