2018
DOI: 10.1016/j.tmaid.2018.05.017
|View full text |Cite
|
Sign up to set email alerts
|

Acquisition of enteric pathogens by pilgrims during the 2016 Hajj pilgrimage: A prospective cohort study

Abstract: The acquisition of diarrhea associated E coli by Hajj pilgrims is of major concern given the high prevalence rate of third-generation cephalosporin-resistant E. coli in Saudi Arabia.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

5
19
3

Year Published

2018
2018
2024
2024

Publication Types

Select...
4
2

Relationship

2
4

Authors

Journals

citations
Cited by 25 publications
(27 citation statements)
references
References 19 publications
5
19
3
Order By: Relevance
“…This acquisition of E. coli is worrying and deserves further investigation aimed at evaluating antibiotic resistance in these bacteria, since one study conducted in medical students revealed a 35% acquisition rate of extended-spectrum beta-lactamase-producing Enterobacteriae [8]. We found no significant association between diarrhoea and E. coli carriage in our study, in contrast with other studies where EAEC has been reported to be frequently associated with diarrhoea in travellers returning from various geographical areas [25][26][27][28][29]. This may be explained either by asymptomatic colonisation or by prolonged nucleic acid shedding in the absence of viable pathogens.…”
Section: Discussioncontrasting
confidence: 98%
See 2 more Smart Citations
“…This acquisition of E. coli is worrying and deserves further investigation aimed at evaluating antibiotic resistance in these bacteria, since one study conducted in medical students revealed a 35% acquisition rate of extended-spectrum beta-lactamase-producing Enterobacteriae [8]. We found no significant association between diarrhoea and E. coli carriage in our study, in contrast with other studies where EAEC has been reported to be frequently associated with diarrhoea in travellers returning from various geographical areas [25][26][27][28][29]. This may be explained either by asymptomatic colonisation or by prolonged nucleic acid shedding in the absence of viable pathogens.…”
Section: Discussioncontrasting
confidence: 98%
“…We observed a low rate of EAEC (4.0%) but a relatively high rate of EPEC (19.2%) carriage in asymptomatic students before travel, in marked contrast with recent findings describing rates of 1-2% in pre-travel stools of Finish travellers using a validated qPCR multiplex assay [24]. High rates of both EAEC (17.5%) and EPEC (14.0%) were also observed in asymptomatic Hajj pilgrims departing from Marseille to Saudi Arabia [25]. Such high rates of EPEC in both asymptomatic medical students and an older Muslim population from Marseille at baseline warrants further investigation in different populations, to better understand the local epidemiology of EPEC in southern France.…”
Section: Discussioncontrasting
confidence: 80%
See 1 more Smart Citation
“…Twenty-one percent of Iranian female pilgrims suffered from gastroenteritis during the 2011 Hajj [50]. In 2013, 23.3% pilgrims from Marseille, France, had diarrhea during the Hajj [51] while a 13.7% prevalence was recorded in 2016 [52]. In the latter study, Escherichia coli was the predominant pathogen isolated from pilgrims by PCR.…”
Section: Gastrointestinal Diseases At the Hajjmentioning
confidence: 82%
“…In the latter study, Escherichia coli was the predominant pathogen isolated from pilgrims by PCR. Enteropathogenic E. coli, enteroaggregative E. coli, and Shiga-like toxin-producing E. coli were acquired by 29.9%, 10.2%, and 6.5% pilgrims, respectively [52]. Among persons infected during the 2011-2013 Hajj and hospitalized in Saudi hospitals, the pathogens responsible for enteric infection were mostly bacteria, with a prevalence of Salmonella spp.…”
Section: Gastrointestinal Diseases At the Hajjmentioning
confidence: 99%