Acral manifestations of soft tissue tumors

Paral, Kristen M.; Petronic‐Rosic, Vesna

doi:10.1016/j.clindermatol.2016.09.012

Cited by 9 publications

(5 citation statements)

References 67 publications

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“…A potential explanation should be a statistical histological subtype preponderance of clear cell, epithelioid, and synovial sarcomas, which may affect younger patients with a lower incidence in DESTS sarcomas of myxoid liposarcomas and liposarcomas, usually developing in older patients . Histological preponderance might also explain DESTS male patient preponderance and impact on prognosis compared to women . Distal extremity sarcomas studies also concluded to having worse outcomes in older and male patients .…”

Section: Discussionmentioning

confidence: 99%

Distal extremities soft tissue sarcomas: Are they so different from other limb localizations?

Mattei

Brouste

Terrier

et al. 2019

Journal of Surgical Oncology

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Background and Objectives Soft tissue sarcoma localization in distal extremities (DESTS) of the limbs (hand/fingers, and foot/toes) is unusual. The literature is scarce about their behavior and this study was designed to assess their epidemiological characteristics, outcomes, and prognosis compared to other limb localizations (OLSTS). Methods From 1980 to 2010, adult DESTS and OLSTS in 22 centers were included. Demographics, tumor type, treatment modalities, and latest follow‐up status were collected. Primary endpoints were overall survival and local/metastatic recurrence incidences. Results Two hundred five DESTS and 3001 OLSTS were included. The patients were younger, with more female and smaller tumors in DESTS. There were more clear cell/epithelioid sarcomas, synovial sarcomas, and myxoid liposarcomas vs more dedifferentiated liposarcomas in OLSTS. DESTS tumors were less irradiated and more often amputated (24.3% vs 3.4%). The five‐year survival rate was 78.2% compared to 68.6% in OLSTS and after multivariate analysis, STS localization did not impact survival or local/metastatic recurrence. Conclusion Though rare and smaller than other limb localizations, DESTS are to be considered as aggressive. Despite a higher amputation rate, the prognosis remains the same as in OLSTS. Limb sparing vs amputation should be carefully assessed in DESTS, especially if grade 3 or of a poor prognosis histological subtype.

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Section: Discussionmentioning

confidence: 99%

Distal extremities soft tissue sarcomas: Are they so different from other limb localizations?

Mattei

Brouste

Terrier

et al. 2019

Journal of Surgical Oncology

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“…A few cases have been described in adults. There is no sex predilection 11 and no suggestion that antecedent trauma may influence its development. It accounts for about 0.1% of fibrous tumours in children.…”

Section: Discussionmentioning

confidence: 99%

Congenital infantile digital fibromatosis: a case report and review of the literature

2020

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Infantile digital fibromatosis (IDF), also called inclusion body fibromatosis is an uncommon benign tumour occurring in the digits of young children. In about a third of cases, it is congenital and the diagnosis is based on the presence of peculiar intracytoplasmic inclusions on histology. Recurrence rate post-surgery is high. However, spontaneous regression has been reported. We present a case of a 5-month-old infant who had excision of a right second toe mass, which has been present from birth. Histological examination revealed this to be infantile digital fibromatosis. To the best of our knowledge, no report of this has been made in Nigeria. It is important that this diagnosis be entertained in young children with masses on the digits as this will influence the management instituted. Keywords: Fibromatosis; digits; inclusion body.

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“…In a paper presenting ultrasonography findings for soft tissue lesions of the limbs, a proper presumed diagnosis for angiolipomas was reported in 8.3% of 36 angiolipoma cases [4]. Awareness of this tumor is important because of the large numbers of other growths in the differential diagnosis for acral soft tissue tumors, as listed in Table 2 [4,10].…”

Section: Case Discussionmentioning

confidence: 99%