Acral persistent papular mucinosis with pruritic skin lesions

Discrete Acral Papular Mucinosis

“…3,4 Acral papular mucinosis was initially recognized in the early 1990s and has since been a subject of intrigue for dermatologists and researchers alike. It is a rare subtype of localized lichen myxedematosus and the literature suggested its association with monoclonal gammopathy [5][6][7][8] ; however, the exact etiology is unknown. Several studies suggested the association of this entity with an immunologic response to an unknown antigenic stimulus.…”

Acral persistent papular mucinosis: a rare child case report and literature review

“…The small number of reported cases makes the accomplishment of therapeutic trials also difficult ( 15 ). There are anecdotal reports of treatment with topical or intralesional steroids ( 18 ) and tacrolimus ( 3 - 7 ) and electrosurgery ( 19 ), and erbium-YAG (yttrium aluminum garnet) laser ( 4 ) with variable results. These treatments are still in the exploratory stage, and their effects have not been widely recognized and are not reproducible.…”