Acral Pseudolymphomatous Angiokeratoma of Children

Ramsay, B.

doi:10.1001/archderm.1990.01670350140035

Cited by 46 publications

(50 citation statements)

References 3 publications

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“…However, this hypothesis was eliminated by different techniques. Otherwise, the main differential diagnoses are other reactive infiltrates or pseudolymphomas; in children, this particularly refers to the rare entity known as APACHE which was described by Ramsay et al [11,12]. This disorder is characterized by unilateral, often multiple, persistent small angiomatous papules or nodules on the acral regions of the hands and feet [11,12,13,14,15].…”

Section: Discussionmentioning

confidence: 99%

“…Otherwise, the main differential diagnoses are other reactive infiltrates or pseudolymphomas; in children, this particularly refers to the rare entity known as APACHE which was described by Ramsay et al [11,12]. This disorder is characterized by unilateral, often multiple, persistent small angiomatous papules or nodules on the acral regions of the hands and feet [11,12,13,14,15]. As with TLP, the papules may converge to form a plaque or may be arranged in a linear pattern, as it was the case in a 14-year-old girl with asymptomatic red and violaceous papules and nodules on the ring finger of her left hand [15] and in a 3-year-old girl with scaly reddish papules on the dorsum of the right hand [16].…”

Section: Discussionmentioning

confidence: 99%

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Tibial Lymphoplasmacytic Plaque: A New, Illustrative Case of a Recently and Poorly Recognized Benign Lesion in Children

Moulonguet¹,

Hadj‐Rabia²,

Gounod

et al. 2012

Dermatology

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Tibial lymphoplasmacytic plaque (TLP) is a recently recognized clinicopathological entity affecting children and is characterized by a linear, reddish brown plaque on the leg with a dense dermal lymphoplasmacytic infiltrate. No effective treatments are available for this lesion of unknown etiology and its course is chronic. We report a new case in which, for the first time, a causative factor (insect bite) is strongly suspected. The clinical and pathological features of TLP may be misleading for the uninformed dermatologist or pathologist. Therefore, we would like to draw attention to this very distinctive clinicopathological presentation in order to help them recognize it easily and prevent it from being misdiagnosed as an infectious disease or, above all, a cutaneous lymphoma. We will discuss the relationship between TLP and linear acral pseudolymphomatous angiokeratoma of children, a variant of pseudolymphoma localized on acral sites in children which may share some of TLP’s histopathological features.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Tibial Lymphoplasmacytic Plaque: A New, Illustrative Case of a Recently and Poorly Recognized Benign Lesion in Children

Moulonguet¹,

Hadj‐Rabia²,

Gounod

et al. 2012

Dermatology

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“…Acral pseudolymphomatous angiokeratoma of children is a rare entity that was first described by Ramsay et al. , in 1988 4 . Since then, less than 20 cases have been described.…”

Section: Discussionmentioning

confidence: 99%

Acral pseudolymphomatous angiokeratoma of children in an elderly man: report of a case and review of the literature

Chedraoui¹,

J²,

Tamraz³

et al. 2010

Int J Dermatology

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Acral pseudolymphomatous angiokeratoma of children (APACHE) is clinically characterized by angiomatous papules that preferentially affect acral areas of children. It is currently believed to be a variant of pseudolymphoma rather than angiokeratoma. Histopathologically, a mixed inflammatory cell infiltrate comprising B- and T-lymphocytes and a proliferation of thick-walled blood vessels are the hallmark. In the literature, although more adult cases are being described, the clinical, epidemiologic and histopathologic data of this presentation is scant. We report a 76-year-old man who presented with a 5-year history of progressively increasing asymptomatic dusky dome-shaped papules and plaques on his upper and lower extremities. Histology was consistent with APACHE. After reviewing all the adult cases in the literature and comparing them to the classical variant in children, we found no significant difference warranting separating these two variants. We prefer the designation "papular angiolymphoid hyperplasia" to APACHE as it encompasses all the childhood and adult cases involving acral and nonacral sites and highlights the histological and sometimes clinical similarities this entity shares with angiolymphoid hyperplasia with eosinophilia.

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“…Acral pseudolymphomatous angiokeratoma of children, a rare pseudolymphoma, was originally thought to be vascular in nature due to the clinical similarity between angiokeratomas and the papules comprising APACHE . The classic presentation is one of multiple red‐to‐violaceous keratotic papules presenting unilaterally on the acral skin of a child, though nonacral locations have been reported.…”

Section: Discussionmentioning

confidence: 99%

Solitary plaque on the leg of a child: A report of two cases and a brief review of acral pseudolymphomatous angiokeratoma of children and unilesional mycosis fungoides

Evans

Burkhart

Bowers

et al. 2018

Pediatric Dermatology

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Acral pseudolymphomatous angiokeratoma of children (APACHE) and unilesional mycosis fungoides (MF) are two rare dermatoses in the pediatric population which may have overlapping clinical and histopathologic features, making differentiation between these two diagnoses difficult. We present two similar cases of a solitary plaque on the thigh of a child, one representing APACHE and the other representing unilesional MF with granulomatous features, and we provide a brief overview of the clinical and histopathologic features of APACHE and unilesional MF.

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Acral Pseudolymphomatous Angiokeratoma of Children

Cited by 46 publications

References 3 publications

Tibial Lymphoplasmacytic Plaque: A New, Illustrative Case of a Recently and Poorly Recognized Benign Lesion in Children

Tibial Lymphoplasmacytic Plaque: A New, Illustrative Case of a Recently and Poorly Recognized Benign Lesion in Children

Acral pseudolymphomatous angiokeratoma of children in an elderly man: report of a case and review of the literature

Solitary plaque on the leg of a child: A report of two cases and a brief review of acral pseudolymphomatous angiokeratoma of children and unilesional mycosis fungoides

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