Acroangiodermatitis: A Study of Ten Cases

Abstract

Acroangiodermatitis is an uncommon entity with peculiar clinical and histologic features and should be confirmed by histologic tests.

Acroangiodermatite (pseudossarcoma de Kaposi): uma condição raramente reconhecida. Um caso na planta do pé associado a insuficiência venosa crônica

“…12 Histopathologic examination shows proliferation of endothelial cells, newly-formed vessels with thick walls, often in a lobular pattern and surrounded by pericytes in the dermis. Extravasation of red blood cells, hemosiderin pigment deposition, dermal fibrosis, small thrombi in the lumen and superficial perivascular infiltrate of lymphocytes, histiocytes and occasional plasma cells are also found, and may resemble Kaposi´s sarcoma.…”

“…Extravasation of red blood cells, hemosiderin pigment deposition, dermal fibrosis, small thrombi in the lumen and superficial perivascular infiltrate of lymphocytes, histiocytes and occasional plasma cells are also found, and may resemble Kaposi´s sarcoma. 12,13 This, however, has vascular slits, proliferation of fusiform cells and atypical cells, and the vascular hyperplasia is independent of pre-existing vasculature. 12,13 Other vascular tumors may be histologically confused with acroangiodermatitis such as hemangioendothelioma.…”

“…12,13 This, however, has vascular slits, proliferation of fusiform cells and atypical cells, and the vascular hyperplasia is independent of pre-existing vasculature. 12,13 Other vascular tumors may be histologically confused with acroangiodermatitis such as hemangioendothelioma.…”

“…14,15 Given its relative rarity, acroangiodermatitis is often misdiagnosed clinically. 11,12 The histopathological characteristics similar to Kaposi's sarcoma and other vascular tumors may also confuse professionals with little experience. [11][12][13][14][15] A faulty diagnosis can lead to inadequate treatment such as surgery, which often leads to complications.…”

Pseudokaposi's sarcoma: a diagnostic dilemma

“…It is rarely reported in hereditary coagulation defects (carrier of the thrombophilic 20210A mutation in the prothrombin gene and homozygous activated protein C resistance) [2,3]. Most of the cases of acroangiodermatitis have been associated with some signs of venous insufficiency however Barbar et al reported no venous insufficiency in 9 of their 10 case of acroangiodermatitis [4] and few cases of spontaneous presentation have also been reported [5].…”