Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin

Baek, Jin Ok; Lee, Hye Young; Lee, Jong Rok; Roh, Joo Young

doi:10.5021/ad.2008.20.4.216

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Cited by 4 publications

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“…[6] We found Bazex syndrome in two patients with primary tumor of stomach and colon, this association has also been reported in the literature. [17][18] Skin lesions of Bazex usually precede the diagnosis of primary tumor in 65-70%, follow the diagnosis in 10-15% and have concurrent onset in 15-25% of cases. [19] In our study one (50%) patient developed skin lesions seven months prior to the diagnosis of adenocarcinoma stomach, while another patient (50%) had concurrent onset.…”

Section: Discussionmentioning

confidence: 99%

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Chauhan¹

2017

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Section: Discussionmentioning

confidence: 99%

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Chauhan¹

2017

jmscr

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Annular and acral/facial dyskeratotic paraneoplastic disorders

Shah

Truong

Schwartz

et al. 2023

Clinics in Dermatology

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A Review of Nail Changes in Acrokeratosis Paraneoplastica (Bazex Syndrome)

Roy

Lipner

2021

Skin Appendage Disord

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Acrokeratosis paraneoplastica (Bazex syndrome) is a rare paraneoplastic dermatosis associated with internal malignancies. Clinical presentation is characterized by erythematous or violaceous scaly plaques involving the digits, nose, ears, palms, and soles. Nail changes commonly present concurrently with cutaneous manifestations. In this review, we characterize nail changes associated with acrokeratosis paraneoplastica. A total of 48 cases were analyzed. Nail findings were nonspecific, with the most common being nail plate thickening, onycholysis, subungual hyperkeratosis, longitudinal ridging, discoloration, and nail plate loss. In most patients, nail changes involved the majority of fingernails and toenails and most often appeared prior to the diagnosis of malignancy. The most common associated underlying malignancies were squamous cell carcinomas of the head and neck. A diagnosis of acrokeratosis paraneoplastica should be considered in patients with onychodystrophy involving multiple nails with accompanying atypical psoriasiform dermatoses. Screening for internal malignancies may significantly decrease morbidity and mortality for these patients.

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Acrokeratosis Paraneoplastica with Adenocarcinoma of the Colon Treated with Topical Tretinoin

Cited by 4 publications

References 14 publications

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Annular and acral/facial dyskeratotic paraneoplastic disorders

A Review of Nail Changes in Acrokeratosis Paraneoplastica (Bazex Syndrome)

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