Acrometástasis óseas, serie de casos y revisión de la literatura

Echeverri, Pablo; García, María Fernanda; C, Julián Garzón; Morales, Laura Cristina; Botero, Oscar Messa; Zúñiga, María Isabel; Mujica, Cesar José Lozada

doi:10.4067/s0717-93082019000300087

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Few cases of AM of the hand as the initial disease presentation have been reported [ 7 , 11 – 15 ]. Furthermore, oligometastatic NSCLC with only a solitary metastasis at time of diagnosis is rare [ 16 ], and only one case with a digital metastasis as a single secondary lesion has been reported [ 17 ]. This paper reports a rare presentation of a KRAS-mutated lung adenocarcinoma with a solitary bone metastasis in the fourth finger medial phalanx, which was also the first sign of the disease.…”

Section: Introductionmentioning

confidence: 99%

Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report

Pușcașu,

Moinard-Butot,

Antoni

et al. 2023

J Med Case Reports

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Background Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell lung cancer. Case presentation This case report describes an unusual presentation of a Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma with a solitary bone metastasis in the fourth finger medial phalanx, which was also the first sign of the disease, in a 63-year-old Caucasian female patient. Digital surgical amputation was performed. After histopathological confirmation and radiological exclusion of other secondary lesions, chemoimmunotherapy in a first-line setting was initiated. A partial metabolic response in the primary lung lesion was observed after four cycles. Maintenance therapy is currently being continued. Conclusion Solitary digital metastasis is a rare finding in non-small cell lung cancer. Further studies are needed to investigate the mechanisms behind this particular dissemination process.

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