Acrylate and methacrylate allergy: When is patch testing with acrylic acid recommended?

Postoperative contact dermatitis caused by skin adhesives used in orthopedic surgery

“…Furthermore, the allergological tests results in patients with suspicious exposure to acrylates before surgery can be an important factor for deciding whether to use a liquid skin adhesive for the skin closure or not. [ 14 , 15 ]…”

“…Furthermore, the allergological tests results in patients with suspicious exposure to acrylates before surgery can be an important factor for deciding whether to use a liquid skin adhesive for the skin closure or not. [14,15] The risk factors for contact dermatitis include high-risk occupations that result in exposure to antigens (e.g., medical personnel, chemical plant and construction workers, beauticians, and mechanics), advanced age, and a history of atopic dermatitis. [16][17][18][19][20][21] There are reports about allergic contact dermatitis in non-occupational settings after exposure to acrylates or methacrylates in gel nail polish, electrodes of electrocardiogram, and dental prosthesis.…”

“…Although patch tests were not used for the diagnosis of allergic contact dermatitis in this study, patch tests, by 2-hydroxyethyl methacrylate (2-HEMA) or acrylate itself, could be used to detect the hypersensitivity to (meth)acrylates. Furthermore, the allergological tests results in patients with suspicious exposure to acrylates before surgery can be an important factor for deciding whether to use a liquid skin adhesive for the skin closure or not [14,15] …”

A case of allergic contact dermatitis to (meth)acrylates in electrocardiogram electrodes

“…This suggests addition of acrylic acid to a (meth)acrylate series could be useful to avoid false negative results in subjects with eczematous lesions at sites of contact with electrodes. 4,9 In the cases of electrode ADC by acrylic acid reported in literature, acrylic acid was demonstrated in the electrode hydrogel part. [3][4][5] Conversely, in the Ambu WhiteSensor 4831Q electrodes used by our patient there is no hydrogel part and acrylates are contained in the inner adhesive side, confirming the need for precise technical product data sheets, that include impurities as well.…”

Intraocular Acrylic Allergy: Is it Something to Sneeze at?

“…The first report of an acrylic allergy was by Stevenson in 1941 [ 6 ]. Since then, there have been numerous cases of methyl (meth)acrylate (MMA) allergies from various sources [ 7 – 11 ], including electrocardiogram hydrogel and artificial nails [ 12 ]. Although the prevalence of acrylic allergy in the general population is unknown, one study observed a prevalence of 1.0–1.4% in a patch-tested population in Sweden and Singapore [ 13 ].…”