Actinic cheilosis: early intervention prevents malignant transformation

Muthukrishnan, Arvind; Kumar, Laliytha Bijai

doi:10.1136/bcr-2016-218654

Cited by 27 publications

(34 citation statements)

References 11 publications

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“…Our study did not statistically confirm the positive association between smoking and cancer, which is consistent with the results of Muthukrishnan, A. ( 21 , 22 ). According to Nevill et al , tobacco is a potent carcinogen, as is alcohol.…”

Section: Discussionsupporting

confidence: 69%

Importance of Early Detection of Potentially Malignant Lesions in the Prevention of Oral Cancer

et al. 2017

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Objective:The aim of this study was to assess the importance of early diagnosis of potentially malignant lesions in the prevention of oral cancer.Material and methods:In order to achieve the set objectives, we selected our participant pool. Of the 340 patients who came to the initial examination at the Clinic for Oral Medicine and Periodontology, we selected 40 patients with potentially malignant oral lesions (PMOL) of both sexes and of different ages. After an extensive anamnesis and a clinical examination of all mucous membranes, we documented potentially malignant lesions, their localization, subjective and objective symptoms, duration of pathological lesion, and bad habits (smoking and alcohol). All lesions were colored with Toluidine blue, which indicates malignancy in 75% of cases. Patients who had a positive Toluidine blue staining test were sent to biopsy and pathohistological analysis.Results:The most common potentially malignant lesions are Lichen reticularis (25%), Lichen erosivus (20%), and Leukoplakia (15%). The most common localization of lesions is the buccal mucosa bilaterally (26%), buccal mucosa unilaterally (10%), and the lower lip (10%). The staining test with Toluidine blue was positive at 23% PMOLs. In patients with positive Toluidine staining findings, biopsy and pathohistological analysis were performed, which showed that 20% of all lesions are carcinoma (CIS, Baseocellular Carcinoma, Squamocellular Carcinoma), while 14% are mucosal epithelial dysplasia. Statistical analysis confirmed the significance of positive staining of Toluidine blue and Leukoplakia (Spearman’s coefficient = 0.427, p = 0.006, N = 40), and statistically significant positive association of Squamocellular Carcinoma and Toluidine blue staining (Spearman’s coefficient = 0.619, p = 0.000, N = 40).Conclusion:Most oral cancers are caused by potentially malignant lesions, which is why a very detailed clinical examination with the visualization of pathological lesions is very important. Toluidine blue test can be an auxiliary tool for clinical diagnosis but does not replace the pathohistological finding. Biopsy and pathohistological findings are the gold standard in the diagnosis of oral cancers, as confirmed in our research.

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Section: Discussionsupporting

confidence: 69%

Importance of Early Detection of Potentially Malignant Lesions in the Prevention of Oral Cancer

et al. 2017

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“…The organic acid formed in the dental plaque is believed to be a predisposing factor for caries, but this is not completely acceptable because it is a complex combined effect of low pH, calcium, luoride and phosphate that results in the dissolution of minerals in the teeth. (Misra, 2015;Muthukrishnan and Kumar, 2017) The continuous increase of luoride levels at low concentration in plaque luid and saliva is important for caries control (Hicks and Flaitz, 2000;Rohini and Kumar, 2017). Poor sugar level control of diabetes has been associated with mouthdryness due to salivary dysfunction, which predisposes to dental caries.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of dental caries in patients with type II diabetes mellitus

Choudhari¹,

Rajendran²,

Ramamurthy³

2020

ijrps

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Diabetes mellitus, a common disease of the 20th century, has been linked with a higher risk of incidence of caries, gingivitis and periodontal disease. The aim of the study was to evaluate the prevalence of dental caries in patients with type II diabetes mellitus and to compare them to those recorded in a control group with no systemic illnesses. Eighty-six thousand patient records were reviewed between June 2019 to March 2020. A total of 200 diabetic patients and 200 control group patients (without any systemic illness) with age group between 30-60 years were included in the study. Cross verification of data was done using RBS values and the patient's medical history. The collected data were tabulated using Microsoft Excel and analysed using SPSS. Incomplete data were excluded from the study. Statistical analysis was done using a chi-square test. In our study, we observed that diabetic individuals had a higher number of caries than control groups. (p<0.05) Individuals above 50 years of age had a higher number of active caries compared to other groups. (p>0.05) The males affected were higher in number than females. (p>0.05) Most individuals with active caries fell in the RBS range of 200-250 mg/dl. Within the limits of the study, diabetic patients showed an increased number of active caries when compared to the control group. There was no significant association between age, gender and RBS values.

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“…There are three groups in RDC criteria. Group I is myofascial pain dysfunction syndrome (Dharman and Muthukrishnan, 2016;Muthukrishnan et al, 2016;Muthukrishnan and Kumar, 2017).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of TMD in patients visiting private dental institution - A retrospective study

Raj¹,

Maheswari²,

Nivedhitha³

2020

ijrps

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Temporomandibular disorder is a collective term for a group of musculoskeletal and neuromuscular conditions. Patients will complain of pain in the TMJ region and the fatigue of the Cranio cervico facial muscles. The aim of the study was to assess the prevalence of TMD in patients visiting a private dental college. This was a retrospective study. Samples were collected from June 2019 to March 2020. The sample size was 55 patients. Data of Temporomandibular disorders were collected. Excel tabulation was done. Chi-Square test was performed and results were obtained using SPSS software. Out of 55 patients, the prevalence of group I of RDC criteria was 34.5%, prevalence of group II of RDC criteria was 62% and the prevalence of group III of RDC criteria was 3.5%. From the present study, it can be concluded that the prevalence of TMD in patients visiting a private dental College was very less. Group II of our RDC criteria was found to be high, with a percentage of 62%.

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Actinic cheilosis: early intervention prevents malignant transformation

Cited by 27 publications

References 11 publications

Importance of Early Detection of Potentially Malignant Lesions in the Prevention of Oral Cancer

Importance of Early Detection of Potentially Malignant Lesions in the Prevention of Oral Cancer

Prevalence of dental caries in patients with type II diabetes mellitus

Prevalence of TMD in patients visiting private dental institution - A retrospective study

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