Actinic Prurigo, A Variety of Polymorphous Light Eruption

Domincuez, L.; Hojyo, María Teresa

doi:10.1111/j.1365-4362.1982.tb02093.x

Cited by 17 publications

(5 citation statements)

References 4 publications

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“…The variability in the literary data is partly due to nosological problems, namely, whether actinic prurigo (AP), also called hydroa aestivale, is a variant of PLE or a distinct entity (14). Several authors (2, 15, 16), including Hungarians, consider AP to be a variant of PLE. Recent genetic studies (17) support the view that AP possibly represents an HLA‐restricted subset of PLE.…”

Section: Idiopathic Photodermatosesmentioning

confidence: 99%

Photosensitivity skin disorders in childhood

Horkay

Emri

Varga

et al. 2008

Photoderm Photoimm Photomed

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SummaryPhotosensitivity in childhood is caused by a diverse group of diseases. It usually indicates idiopathic photodermatoses, first of all polymorphic light eruption. It may be an early symptom of genetic disorders such as porphyria or very rare genophotodermatoses. Photosensitivity secondary to topical or systemic external agents as well as photoexacerbated dermatoses is not so frequent in childhood. Here we present our experience with childhood photosensitivity skin diseases collected over a 40-year period. L ight-induced skin eruptions are not a common problem in pediatric dermatology. However, the condition often causes trouble and discomfort to the affected child and the parents.The literature on childhood photodermatoses (PDs) is relatively scanty. The incidence of PDs in childhood is much lower than in adults (1). According to the paper published by Jansén (2), photosensitivity started at the age of 15 years or earlier in 26% of the cases out of a total of 370 PD patients. There is also a shortage of primary data on the prevalence of PDs classified recently by Yashar and Lim (3) such as (i) idiopathic PD: polymorphic light eruption (PLE), juvenile spring eruption of the ears (JSE), solar urticaria (SU), hydroa vacciniforme (HV), (ii) photosensitivity secondary to exogenous agents, (iii) cutaneous porphyrias, (iv) genophotodermatoses and (v) photoexacerbated/aggravated disorders. The paper presents experience with PDs in childhood (83 cases) collected at the Department of Dermatology, Debrecen, between 1967 and 2006.The diagnosis in the vast majority of PD cases in children is PLE, whereas the order of other diseases is quite variable depending on geographic and genetic conditions. In the Finnish report (2) mentioned before, PLE was followed by xeroderma pigmentosum (XP) and then erythropoietic protoporphyria (EPP), while no cases were recorded from external photosensitizers. According to other literary data, phototoxic dermatitis occurs relatively often besides idiopathic PDs during childhood (4). Similar to these findings the most frequent diagnosis at our Department of Dermatology was also PLE. However, we recorded a rather high number of EPP cases and some porphyria cutanea tarda (PCT) as well, but only a few cases of XP (Table 1).Diagnosis of PD in childhood is not as easy as in adulthood (5). In the history occasionally (mostly in EPP) a family history is noted, such as in our patient material (6). The clinical picture is featured by various kinds of eruptions localized typically on the sun-exposed skin. The diagnosis in childhood can also be confirmed by phototests. Most informative is the provocation test used to reproduce lesions of idiopathic PDs (5). We perform it with ultraviolet (UV)B and UVA separately (Multitester SBB LT 400; Saalmann, Herford, Germany) (7) according to the protocol of Lehmann et al. (8). Photopatch testing for identifying external photosensitizer(s) is not performed commonly in children. We have not used it in our practice. Concerning laboratory tests, in porphyrias spect...

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Section: Idiopathic Photodermatosesmentioning

confidence: 99%

Photosensitivity skin disorders in childhood

Horkay

Emri

Varga

et al. 2008

Photoderm Photoimm Photomed

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“…11 Transient forms of PLE in the spring are termed benign summer eruption. Actinic prurigo is considered by some to be a 12 This sunlight-induced itchy disorder is strongly associated with HLA-DR4 subtype DRB1*0407 (60-70% of cases), is most common in children, and consists of prurigo lesions on the face and distal limbs.The differential diagnosis is often atopic eczema, but the distribution and exacerbation in summer is helpful diagnostically. Juvenile spring eruption consists of pruritic vesicles or papules affecting the rim of the ears most commonly in boys and is considered by some as a variant of PLE.…”

Section: Acquired Photodermatosesmentioning

confidence: 99%

Sunscreens and the photodermatoses

Lenane

Murphy

2001

Journal of Dermatological Treatment

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The photodermatoses are defined by their clinical features which result from exposure to ultraviolet radiation or visible light. Accurate diagnosis, which is often complicated, is essential to ensure appropriate treatment and protection from precipitating wavelengths. We review the acquired photodermatoses including polymorphic light eruption, hydroa vacciniforme and chronic actinic dermatitis. The genodermatoses including the DNA repair deficiency and melanin-deficient syndromes are discussed, and the best methods for protection of the cutaneous photodermatoses including relevant sunscreen use are elaborated.

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“…In Caucasians it is uncommon, and predominantly affects girls in the first decade of life. Although some have suggested it to be a variant of PLE, 13,14 there is now sufficient data on clinical and investigative grounds to consider it a distinct entity 15–17 . Amerindians, who have a particularly high incidence of this condition, frequently have affected family members.…”

Section: The Photodermatosesmentioning

confidence: 99%